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Recombinant Human IL-29/IFN-lambda 1 Protein, ≥95% (SDS-PAGE), high purity

  • ActiBioPure™
  • Animal Free
  • Azide Free
  • Bioactive
  • Carrier Free
  • High performance
  • ≥95%(SDS-PAGE)
Features and benefits
  • Expression System: HEK293
  • Accession #: Q8IU54
  • Protein Tag: C-His
  • Bioactivity: Measured in antiviral assays using HepG2 cells infected with vesicular stomatitis virus. The ED50 for this effect is typically 5-20 ng/mL.
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp147538
Grouped product items
SKUSizeAvailabilityPrice Qty
rp147538-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
rp147538-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$279.90
rp147538-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$449.90
rp147538-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

Animal Free, ≥95% (SDS-PAGE), Active, 293F, C-His tag, 20-200 aa

Basic Description

Product NameRecombinant Human IL-29/IFN-lambda 1 Protein, ≥95% (SDS-PAGE), high purity
Synonymscytokine Zcyto21; IFNL1; IFN-lambda 1; IFN-lambda-1; IL29; IL-29; interferon lambda-1; interferon, lambda 1; interleukin 29 (interferon, lambda 1); interleukin-29; ZCYTO21
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, High performance
Product Description

Purity
≥95% SDS-PAGE.
Endotoxin level
<0.1 EU/µg
Function
Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE)
Purity≥95% (SDS-PAGE)
BioactivityMeasured in antiviral assays using HepG2 cells infected with vesicular stomatitis virus. The ED50 for this effect is typically 5-20 ng/mL.
Endotoxin Concentration<0.1 EU/μg
Expression SystemHEK293
SpeciesHuman
Amino Acids20-200 aa
SequenceGPVPTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFRLLTRDLKYVADGNLCLRTSTHPESTHHHHHH
Protein TagC-His
Accession #Q8IU54
Predicted molecular weight22 kDa
SDS-PAGE27-37 kDa under reducing conditions.

Images

Recombinant Human IL-29/IFN-lambda 1 Protein (rp147538) - SDS-PAGE
3 μg/lane of Recombinant IL-29/IFN-lambda 1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 27 - 37 kDa.

Product Specifications

FormLyophilized
ReconstitutionReconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404972Certificate of AnalysisApr 30, 2024 rp147538
ZJ24F0404971Certificate of AnalysisApr 30, 2024 rp147538
ZJ24F0404970Certificate of AnalysisApr 30, 2024 rp147538

Related Documents

References

1. Sheppard, Paul P and 25 more authors..  (2003)  IL-28, IL-29 and their class II cytokine receptor IL-28R..  Nature immunology,      [PMID:12469119]
2. Kotenko, Sergei V SV and 9 more authors..  (2003)  IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex..  Nature immunology,      [PMID:12483210]
3. Grimwood, Jane J and 97 more authors..  (2004)  The DNA sequence and biology of human chromosome 19..  Nature,    (1):   [PMID:15057824]
4. Miknis, Zachary J ZJ and 5 more authors..  (2010)  Crystal structure of human interferon-λ1 in complex with its high-affinity receptor interferon-λR1..  Journal of molecular biology,    (10):   [PMID:20934432]

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