Recombinant Human IL-29/IFN-lambda 1 Protein, ≥95% (SDS-PAGE), high purity
ActiBioPure™
Animal Free
Azide Free
Bioactive
Carrier Free
High performance
≥95%(SDS-PAGE)
Features and benefits
Expression System: HEK293
Accession #: Q8IU54
Protein Tag: C-His
Bioactivity: Measured in antiviral assays using HepG2 cells infected with vesicular stomatitis virus. The ED50 for this effect is typically 5-20 ng/mL.
Endotoxin Concentration: <0.1 EU/μg
Item Number
rp147538
Grouped product items
SKU
Size
Availability
Price
Qty
rp147538-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
rp147538-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$279.90
rp147538-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$449.90
rp147538-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, High performance
Product Description
Purity ≥95% SDS-PAGE. Endotoxin level <0.1 EU/µg Function Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Recombinant Human IL-29/IFN-lambda 1 Protein (rp147538) - SDS-PAGE 3 μg/lane of Recombinant IL-29/IFN-lambda 1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 27 - 37 kDa.
Product Specifications
Form
Lyophilized
Reconstitution
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.
Certificates
Certificate of Analysis(COA)
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1.Sheppard, Paul P and 25 more authors.. (2003) IL-28, IL-29 and their class II cytokine receptor IL-28R.. Nature immunology, [PMID:12469119]
2.Kotenko, Sergei V SV and 9 more authors.. (2003) IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.. Nature immunology, [PMID:12483210]
3.Grimwood, Jane J and 97 more authors.. (2004) The DNA sequence and biology of human chromosome 19.. Nature, (1):[PMID:15057824]
4.Miknis, Zachary J ZJ and 5 more authors.. (2010) Crystal structure of human interferon-λ1 in complex with its high-affinity receptor interferon-λR1.. Journal of molecular biology, (10):[PMID:20934432]
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