| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| rp147615-10μg | 10μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 | |
| rp147615-25μg | 25μg | In stock | $169.90 | |
| rp147615-100μg | 100μg | In stock | $499.90 | |
| rp147615-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,559.90 |
Animal Free, >95% SDS-PAGE, Active, E.coli, No tag, Pro29-Met212
| Product Name | Recombinant Human IL-6 Protein, ＞95% SDS-PAGE, high purity |
|---|---|
| Synonyms | B-cell differentiation factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CTL differentiation factor ; HSF; hybridoma growth factor; IFNB2; IFN-beta-2; IL6; IL-6; Interferon beta-2; interleukin 6 (interferon, beta 2); interleukin BSF-2; interleukin-6; |
| Grade | ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, 高性能 |
| Product Description | Purity >95% SDS-PAGE. Protein Content and Purity (typically = 95%) determined by reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm. Additional sequence information This product is for the mature full length protein. The signal peptide is not included. Function Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. Post-translational:N- and O-glycosylated. |
| Specifications & Purity | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE) |
| Purity | ＞95% SDS-PAGE |
| Bioactivity | Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is typically less than 0.6 ng/mL. |
| Endotoxin Concentration | < 1 EU/µg |
| Expression System | E.coli |
| Species | Human |
| Amino Acids | 29-212 aa |
| Sequence | PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEKDGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPDPTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM |
| Protein Tag | No tag |
| Accession # | P05231 |
| Predicted molecular weight | 20.9 kDa |
| SDS-PAGE | 20.6 kDa, under reducing conditions; 20.6 kDa, under non-reducing conditions. |
Recombinant Human IL-6 Protein (rp147615) - Protein Bioactivity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is typically less than 0.6 ng/mL.
Recombinant Human IL-6 Protein (rp147615) - SDS-PAGE
2 μg/lane of Recombinant Human IL-6 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 20.6 kDa.
| Form | Lyophilized |
|---|---|
| Reconstitution | After receiving lyophilized powder protein, centrifuge first, and reconstitute at 100ug/mL in sterile PBS. |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Stable for 12 months from the date of receipt of the product under proper storage andhandling conditions. Avoid repeated freeze-thaw cycles. |
Enter Lot Number to search for COA:
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| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1101728 | Certificate of Analysis | Nov 20, 2023 | rp147615 |
| ZJ23F1101727 | Certificate of Analysis | Nov 20, 2023 | rp147615 |
| ZJ23F0800893 | Certificate of Analysis | Aug 23, 2023 | rp147615 |
| ZJ23F0800894 | Certificate of Analysis | Aug 23, 2023 | rp147615 |
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