Recombinant Human LILRB1/CD85j/ILT2 Protein, ≥95% (SDS-PAGE), high purity

Features and benefits
  • Expression System: HEK293
  • Accession #: Q8NHL6
  • Protein Tag: C-His
  • Bioactivity: When Recombinant Human LILRB1/CD85j/ILT2 is coated at 2 µg/mL, Recombinant Human Angiopoietin-like Protein 7/ANGPTL7 binds with a typical ED50 of 0.02-0.2 μg/mL.
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp148284
Grouped product items
SKUSizeAvailabilityPrice Qty
rp148284-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
rp148284-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90
rp148284-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$659.90
rp148284-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$4,999.90

Animal Free, ≥95% (SDS-PAGE), Active, 293F, C-His tag, 24-458 aa

Basic Description

Product NameRecombinant Human LILRB1/CD85j/ILT2 Protein, ≥95% (SDS-PAGE), high purity
SynonymsLeukocyte Immunoglobulin-like Receptor, Subfamily A (with TM domain), Member 1 | CD85 antigen-like family member J | CD85j antigen | CD85j | Ig-like transcript 2 | ILT2 | ILT-2 | FLJ37515 | Immunoglobulin-like transcript 2 | leukocyte Ig-like receptor-1 |
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description

Purity
≥95% SDS-PAGE.
Endotoxin level
<0.1 EU/µg
Function
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity≥95% (SDS-PAGE)
BioactivityWhen Recombinant Human LILRB1/CD85j/ILT2 is coated at 2 µg/mL, Recombinant Human Angiopoietin-like Protein 7/ANGPTL7 binds with a typical ED50 of 0.02-0.2 μg/mL.
Endotoxin Concentration<0.1 EU/μg
Expression SystemHEK293
SpeciesHuman
Amino Acids24-458 aa
SequenceGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHHHHHHH
Protein TagC-His
Accession #Q8NHL6
Predicted molecular weight48 kDa
SDS-PAGE60.0 - 80.0 kDa, under reducing conditions; 60.0 - 80.0 kDa, under non-reducing conditions.

Images

Recombinant Human LILRB1/CD85j/ILT2 Protein (rp148284) - Protein Bioactivity
When Recombinant Human LILRB1/CD85j/ILT2 Protein (rp148284) is coated at 4.0 µg/mL, Biotinylated Recombinant Human Angiopoietin-like 7/ANGPTL7 Protein (rp142833) binds with the ED ₅₀ of 2.0 μg/mL.

Recombinant Human LILRB1/CD85j/ILT2 Protein (rp148284) - SDS-PAGE
3 μg/lane of Recombinant Human LILRB1/CD85j/ILT2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 60.0 - 80.0 kDa.

Product Specifications

FormLyophilized
ReconstitutionReconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0607354Certificate of AnalysisJun 28, 2024 rp148284
ZJ24F0607353Certificate of AnalysisJun 28, 2024 rp148284
ZJ24F0607352Certificate of AnalysisJun 28, 2024 rp148284

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