Recombinant Human LTBR Protein, >95% (SDS-PAGE), high purity

Features and benefits
  • Expression System: HEK293
  • Accession #: P36941
  • Protein Tag: C-Fc & His
  • Bioactivity: Immobilized Recombinant Human LIGHT at 1 μg/mL (100 μL/well) can bind Recombinant Human LTBR with a linear range of 15-55 ng/mL.
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp148424
Grouped product items
SKUSizeAvailabilityPrice Qty
rp148424-10μg
10μg
In stock
$109.90
rp148424-50μg
50μg
In stock
$269.90
rp148424-100μg
100μg
In stock
$399.90
rp148424-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,399.90

Animal Free, >95% (SDS-PAGE), Active, HEK 293F, C-Fc & His tag, 31-227aa

Basic Description

Product NameRecombinant Human LTBR Protein, >95% (SDS-PAGE), high purity
SynonymsLymphotoxin-beta receptor | TNFR-III | TNF-RIII | Tumor necrosis factor C receptor | Tumor necrosis factor receptor 2-related protein | Tumor necrosis factor receptor type III
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description

Purity
>95% SDS-PAGE.
Additional sequence information
Extracellular domain fused with Fc tag at the C-terminus.

Function
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity>95% (SDS-PAGE)
BioactivityImmobilized Recombinant Human LIGHT at 1 μg/mL (100 μL/well) can bind Recombinant Human LTBR with a linear range of 15-55 ng/mL.
Endotoxin Concentration<0.1 EU/μg
Expression SystemHEK293
SpeciesHuman
Amino Acids31-227aa
SequenceQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
Protein TagC-Fc & His
Accession #P36941
Predicted molecular weight49kDa
SDS-PAGE61.5 kDa, under reducing conditions.

Images

Recombinant Human LTBR Protein (rp148424) - Protein Bioactivity
Immobilized Recombinant Human LIGHT at 1.0 μg/mL can bind Recombinant Human LTBR Protein (rp148424) with a linear range of 15.0 - 55.0 ng/mL.

Recombinant Human LTBR Protein (rp148424) - SDS-PAGE
3 μg/lane of Recombinant Human LTBR Protein was resolved with SDS-PAGE under reducing (R) condition and visualized by Coomassie® Blue staining, showing a band at 61.5 kDa under reducing condition.

Product Specifications

FormLyophilized
ReconstitutionReconstitute in water to a concentration of 0.1-0.5 mg/ml.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20~-80℃ for more than 1 year.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0102339Certificate of AnalysisJan 30, 2024 rp148424
ZJ24F0102340Certificate of AnalysisJan 30, 2024 rp148424
ZJ24F0102341Certificate of AnalysisJan 30, 2024 rp148424

Related Documents

References

1. Crowe, P D PD and 9 more authors..  (1994)  A lymphotoxin-beta-specific receptor..  Science (New York, N.Y.),    (29):   [PMID:8171323]
2. Baens, M M, Chaffanet, M M, Cassiman, J J JJ, van den Berghe, H H and Marynen, P P..  (1993)  Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid..  Genomics,      [PMID:8486360]
3. Nakano, H H and 6 more authors..  (1996)  TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor..  The Journal of biological chemistry,    (21):   [PMID:8663299]
4. Matsumoto, M M and 10 more authors..  (1997)  Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor..  Journal of virology,      [PMID:8995654]
5. Mizushima, S S and 8 more authors..  (1998)  Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5)..  Gene,    (30):   [PMID:9511754]
6. Krajewska, M M and 11 more authors..  (1998)  TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues..  The American journal of pathology,      [PMID:9626059]
7. Wu, M Y MY, Wang, P Y PY, Han, S H SH and Hsieh, S L SL..  (1999)  The cytoplasmic domain of the lymphotoxin-beta receptor mediates cell death in HeLa cells..  The Journal of biological chemistry,    (23):   [PMID:10207006]
8. Rooney, I A IA and 8 more authors..  (2000)  The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells..  The Journal of biological chemistry,    (12):   [PMID:10799510]
9. Scherer, Steven E SE and 216 more authors..  (2006)  The finished DNA sequence of human chromosome 12..  Nature,    (16):   [PMID:16541075]

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