Recombinant Human p27 KIP 1 Protein, >95% SDS-PAGE, high purity

Features and benefits
  • Expression System: E. coli
  • Protein Tag: N-His
  • Endotoxin Concentration: <1.0 EU/μg
Item Number
rp176706
Grouped product items
SKUSizeAvailabilityPrice Qty
rp176706-10μg
10μg
In stock
$59.90
rp176706-100μg
100μg
In stock
$359.90
rp176706-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90

Carrier Free, >95% SDS-PAGE, E.coli, His, 1-198 aa

Basic Description

Product NameRecombinant Human p27 KIP 1 Protein, >95% SDS-PAGE, high purity
SynonymsCyclin-dependent kinase inhibitor 1B | Cyclin-dependent kinase inhibitor p27 | p27Kip1 | AA408329 | AI843786 | Cdki1b | CDKN 1B | CDKN 4 | CDKN1B | CDKN4 | CDN1B_HUMAN | Cyclin Dependent Kinase Inhibitor 1B | Cyclin dependent kinase inhibitor p27 | Cyclin
GradeAzide Free, Carrier Free
Product Description

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skeletal muscle. CDKN1B is a potent inhibitor of Cyclin E- and Cyclin A-CDK2 complexes. CDKN1B forms a complex with Cyclin Type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. In addition, CDKN1B acts as an inhibitor or an activator of Cyclin Type D-CDK4 complexes depending on its phosphorylation state and stoichometry.

Specifications & PurityCarrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity>95% SDS-PAGE
Endotoxin Concentration<1.0 EU/μg
Expression SystemE. coli
Amino Acids1-198 aa
SequenceMGSSHHHHHHSSGLVPRGSHMSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
Protein TagN-His
Predicted molecular weight24.2 kDa
SDS-PAGE29.7 kDa, reducing conditions; 26.7 and 29.4 kDa,non-reducing condition

Images

Recombinant Human p27 KIP 1 Protein (rp176706) - SDS-PAGE
3 μg/lane of Recombinant Human p27 KIP 1 Protein was resolved with SDS-PAGE under reducing (R) visualized by Coomassie® Blue staining, showing a band at 29.7 kDa under reducing conditions.

Product Specifications

FormLyophilized
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilu
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C stable up to 1 year. Avoid freeze / thaw cycle.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0102361Certificate of AnalysisJan 30, 2024 rp176706
ZJ24F0102360Certificate of AnalysisJan 30, 2024 rp176706
ZJ24F0102359Certificate of AnalysisJan 30, 2024 rp176706

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