Recombinant Human Pentraxin 3/TSG-14 Protein, ≥95% (SDS-PAGE), high purity

Features and benefits
  • Expression System: HEK293
  • Accession #: P26022
  • Protein Tag: C-His
  • Bioactivity: Immobilized Human FGF2 Protein at 1.0 µg/mL(100 µL/well) can bind PTX3 with a linear range of 1.0-20 ng/mL.
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp150067
Grouped product items
SKUSizeAvailabilityPrice Qty
rp150067-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
rp150067-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$349.90
rp150067-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$589.90
rp150067-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,429.90

Animal Free, ≥95% (SDS-PAGE), Active, 293F, C-His tag, 18-381 aa

Basic Description

Product NameRecombinant Human Pentraxin 3/TSG-14 Protein, ≥95% (SDS-PAGE), high purity
Synonymsalpha-induced protein 5 | pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor | Pentaxin-related protein PTX3 | Pentraxin 3 | pentraxin 3, long | pentraxin-3 | pentraxin-related gene, rapidly induced by IL-1 beta | pentraxin-related
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description

Purity
≥95% (SDS-PAGE)
Endotoxin level
<0.1 EU/μg
Function
Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity≥95% (SDS-PAGE)
BioactivityImmobilized Human FGF2 Protein at 1.0 µg/mL(100 µL/well) can bind PTX3 with a linear range of 1.0-20 ng/mL.
Endotoxin Concentration<0.1 EU/μg
Expression SystemHEK293
SpeciesHuman
Amino Acids18-381 aa
SequenceENSDDYDLMYVNLDNEIDNGLHPTEDPTPCACGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQRLREELGRLAESLARPCAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVSHHHHHH
Protein TagC-His
Accession #P26022
Predicted molecular weight40 kDa
SDS-PAGE45.0 - 50.0 kDa, under reducing conditions; 43.0 - 48.0 & 75.0 - 80.0 kDa, under non-reducing conditions.

Images

Recombinant Human Pentraxin 3/TSG-14 Protein (rp150067) - Protein Bioactivity
Immobilized Human FGF2 Protein at 1.0 ug/mL can bind Recombinant Human Pentraxin 3/TSG-14 Protein (rp150067) with a linear range of 1.0 - 20.0 ng/mL. The ED₅₀ for this effect is 36.12 ng/mL.

Recombinant Human Pentraxin 3/TSG-14 Protein (rp150067) - SDS-PAGE
3 μg/lane of Recombinant Human Pentraxin 3/TSG-14 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 45.0 - 50.0 kDa under reducing conditions and 43.0 - 48.0 & 75.0 - 80.0 kDa under non-reducing conditions.

Recombinant Human DLL4 Protein (rp181238) - Binding Activity
Immobilized Recombinant Human DLL4 Protein (rp181238) at 5.0 μg/mL can bind Recombinant Human Notch-1 Protein (rp183726) with the EC₅₀ of 26.54 ng/mL.

Product Specifications

FormLyophilized
ReconstitutionReconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404978Certificate of AnalysisApr 30, 2024 rp150067
ZJ24F0404977Certificate of AnalysisApr 30, 2024 rp150067
ZJ24F0404976Certificate of AnalysisApr 30, 2024 rp150067

Related Documents

References

1. Breviario, F F and 9 more authors..  (1992)  Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component..  The Journal of biological chemistry,    (5):   [PMID:1429570]
2. Lee, G W GW, Goodman, A R AR, Lee, T H TH and Vilcek, J J..  (1994)  Relationship of TSG-14 protein to the pentraxin family of major acute phase proteins..  Journal of immunology (Baltimore, Md. : 1950),    (15):   [PMID:7523502]
3. Lee, G W GW, Lee, T H TH and Vilcek, J J..  (1993)  TSG-14, a tumor necrosis factor- and IL-1-inducible protein, is a novel member of the pentaxin family of acute phase proteins..  Journal of immunology (Baltimore, Md. : 1950),    (1):   [PMID:7679696]
4. Introna, M M and 5 more authors..  (1993)  IL-1 inducible genes in human umbilical vein endothelial cells..  European heart journal,      [PMID:8131794]
5. Mantovani, Alberto A, Garlanda, Cecilia C and Bottazzi, Barbara B..  (2003)  Pentraxin 3, a non-redundant soluble pattern recognition receptor involved in innate immunity..  Vaccine,    (1):   [PMID:12763682]
6. Muzny, Donna M DM and 113 more authors..  (2006)  The DNA sequence, annotation and analysis of human chromosome 3..  Nature,    (27):   [PMID:16641997]

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