Recombinant Human SIRP beta 1/CD172b Protein, ≥95% (SDS-PAGE), high purity

Features and benefits
  • Expression System: HEK293
  • Protein Tag: C-His
  • Bioactivity: When Recombinant Human SIRP beta 1/CD172b is immobilized at 1 µg/mL (100 µL/well), Recombinant Human SP‑D binds with an ED50 of 0.1-0.8 μg/mL
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp167082
Grouped product items
SKUSizeAvailabilityPrice Qty
rp167082-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
rp167082-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$469.90
rp167082-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$759.90
rp167082-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$4,999.90

Animal Free, ≥95% (SDS-PAGE), Active, HEK293, C-His tag, 30-371 aa

Basic Description

Product NameRecombinant Human SIRP beta 1/CD172b Protein, ≥95% (SDS-PAGE), high purity
SynonymsCD172 antigen like family member B; CD172b; CD172b antigen; DKFZp686A05192; Signal regulatory protein beta 1; SIRP BETA 1; SIRP beta 1 isoform 3; SIRPB1; SIRP-BETA-1
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description

Purity
≥95% (SDS-PAGE)
Endotoxin level
<0.1 EU/μg
Function
The protein encoded by the SIRPß1 gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins which are known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPß1 was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity≥95% (SDS-PAGE)
BioactivityWhen Recombinant Human SIRP beta 1/CD172b is immobilized at 1 µg/mL (100 µL/well), Recombinant Human SP‑D binds with an ED50 of 0.1-0.8 μg/mL
Endotoxin Concentration<0.1 EU/μg
Expression SystemHEK293
Amino Acids30-371 aa
SequenceEDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAVRATPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEIAHITLQGDPLRGTANLSEAIRVPPTLEVTQQPMRAENQANVTCQVSNFYPRGLQL
Protein TagC-His
Predicted molecular weight38 kDa
SDS-PAGE55-60 kDa, under reducing conditions

Images

Recombinant Human SIRP beta 1/CD172b Protein (rp167082) - Protein Bioactivity
When Recombinant Human SIRP beta 1/CD172b Protein (rp167082) is immobilized at 1.0 µg/mL, Recombinant Human SP‑D binds with an ED₅₀ of 0.93 μg/mL.

Recombinant Human SIRP beta 1/CD172b Protein (rp167082) - SDS-PAGE
3 μg/lane of Recombinant Human SIRP beta 1/CD172b Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 45.0 - 55.0 kDa.

Product Specifications

FormLyophilized
ReconstitutionReconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404855Certificate of AnalysisApr 26, 2024 rp167082
ZJ24F0404854Certificate of AnalysisApr 26, 2024 rp167082
ZJ24F0404853Certificate of AnalysisApr 26, 2024 rp167082

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