Recombinant Human TFF2 Protein, >97%(SDS-PAGE and HPLC), high purity

Features and benefits
  • Expression System: E.coli
  • Accession #: Q03403
  • Protein Tag: No tag
  • Bioactivity: Fully biologically active when compared to standard. The ED₅₀ as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 ng/ml, corresponding to a specific activity of > 1.0 × 10⁵ IU/mg.
  • Endotoxin Concentration: <1.0 EU/μg
Item Number
rp152239
Grouped product items
SKUSizeAvailabilityPrice Qty
rp152239-10μg
10μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$69.90
rp152239-50μg
50μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$329.90
rp152239-100μg
100μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$599.90
rp152239-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90
rp152239-500μg
500μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,739.90

Animal Free, >97%(SDS-PAGE and HPLC), Active, E.coli, No tag, 24-129 aa

Basic Description

Product NameRecombinant Human TFF2 Protein, >97%(SDS-PAGE and HPLC), high purity
SynonymsSML 1 | SML1 | SP | Spasmolysin | Spasmolytic polypeptide | spasmolytic protein 1 | TFF 2 | TFF2 | TFF2_HUMAN | Trefoil factor 2 | trefoil factor 2 (spasmolytic protein 1) | Trefoil factor 2 precursor | SP | Spasmolysin | Spasmolytic polypeptide
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, High Performance
Product Description

Purity

> 97 % by SDS-PAGE and HPLC analyses


Additional sequence information

This product is the mature full length protein from aa 24 to 129. The signal peptide is not included.


Function

Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥97%(SDS-PAGE&HPLC)
Purity>97%(SDS-PAGE and HPLC)
BioactivityFully biologically active when compared to standard. The ED₅₀ as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 ng/ml, corresponding to a specific activity of > 1.0 × 10⁵ IU/mg.
Endotoxin Concentration<1.0 EU/μg
Expression SystemE.coli
SpeciesHuman
Amino Acids24-129 aa
SequenceEKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
Protein TagNo tag
Accession #Q03403
Predicted molecular weight12.0 kDa

Images

Recombinant Human TFF2 Protein (rp152239)-Protein Bioactivity
Fully biologically active when compared to standard. The ED₅₀ as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 ng/mL, corresponding to a specific activity of > 1.0 × 10⁵ IU/mg.

Recombinant Human TFF2 Protein (rp152239) - SDS-PAGE
Recombinant Human TFF2 Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a single band at 12.0 kDa.

Product Specifications

FormLyophilized
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportion
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconst

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
ZJ23F0600362Certificate of AnalysisMar 26, 2024 rp152239
ZJ23F0600363Certificate of AnalysisMar 26, 2024 rp152239
ZJ23F0600364Certificate of AnalysisMar 26, 2024 rp152239
ZJ23F0600365Certificate of AnalysisMar 26, 2024 rp152239

Related Documents

References

1. Tomasetto, C C and 6 more authors..  (1990)  hSP, the domain-duplicated homolog of pS2 protein, is co-expressed with pS2 in stomach but not in breast carcinoma..  The EMBO journal,      [PMID:2303034]
2. Seib, T T and 8 more authors..  (1997)  The three human trefoil genes TFF1, TFF2, and TFF3 are located within a region of 55 kb on chromosome 21q22.3..  Genomics,    (15):   [PMID:9070946]
3. Berry, A A and 16 more authors..  (2000)  Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region..  Genomics,    (15):   [PMID:10950923]

Solution Calculators