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Recombinant Human TNF-alpha Protein, ≥95% (SDS-PAGE), high purity

≥95%(SDS-PAGE)
Lot by Lot

Features and benefits

Expression System: E.coli
Accession #: P01375
Protein Tag: No tag
Bioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.05 ng/mL.
Endotoxin Concentration: <0.1 EU/μg

Item Number

rp152506

Grouped product items
SKU	Size	Availability	Price
rp152506-10μg	10μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$79.90
rp152506-50μg	50μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$189.90
rp152506-100μg	100μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$289.90
rp152506-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,999.90

GMP, ≥95% (SDS-PAGE), Active, E.coli, No tag, 77-233 aa

View related series

Click to view protein information: TNF

Accession#:P01375 Gene ID:7124 TNF TNF-alpha TNFa TNFα

Basic Description

Product Name	Recombinant Human TNF-alpha Protein, ≥95% (SDS-PAGE), high purity
Synonyms	APC1 protein \| Cachectin \| Cachetin \| DIF \| TNF \| TNF, monocyte-derived \| TNFA \| TNF-A \| TNFalpha \| TNF-alpha \| TNF-alphacachectin \| TNFATNF, macrophage-derived \| TNFG1F \| TNFSF1A \| TNFSF2 \| TNFSF2TNF superfamily, member 2 \| tumor necrosis factor (TNF sup
Grade	ActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance
Product Description	Tumor necrosis factor-α (TNFα) is a kind of cytokine mainly produced by macrophages and monocytes, which can participate in the immune response and inflammatory response of the body. The increase of TNFα value is closely related to sepsis, malignant tumor, heart failure and chronic inflammatory diseases, which can be used as an evaluation index of disease condition, treatment effect and prognosis. At the same time, TNFα is also a key target of autoimmune diseases. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia. Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
Specifications & Purity	Carrier Free, GMP, Bioactive, ActiBioPure™, High performance, Animal Free, ≥95%(SDS-PAGE), Lot by Lot
Purity	≥95% (SDS-PAGE)
Bioactivity	Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.05 ng/mL.
Endotoxin Concentration	<0.1 EU/μg
Expression System	E.coli
Species	Human
Amino Acids	77-233 aa
Sequence	VRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVV PSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSP CQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQV YFGIIAL
Protein Tag	No tag
N-terminal Sequence	Val
Protein Length	Full length protein
Accession #	P01375
Source	Recombinant
Predicted molecular weight	17.4 kD

Images

Recombinant Human TNF-alpha Protein (rp152506)-Protein Bioactivity
Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The EC₅₀ for this effect is typically <0.05ng/mL.

Recombinant Human TNF-alpha Protein (rp152506)-SDS-PAGE
2μg/lane of Recombinant Human TNF-alpha was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing a single band at 16 kDa.

Product Specifications

Form	liquid
Concentration	Lot by Lot
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Stability And Storage	Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
ZJ23F0700612	Certificate of Analysis	Apr 25, 2024	rp152506
ZJ23F0700613	Certificate of Analysis	Apr 25, 2024	rp152506
ZJ23F0300076	Certificate of Analysis	Jan 25, 2024	rp152506
ZJ23F0300077	Certificate of Analysis	Jan 25, 2024	rp152506
ZJ23F0300078	Certificate of Analysis	Mar 25, 2023	rp152506

FAQs and Articles

References

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