| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| rp152513-10μg | 10μg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 | |
| rp152513-50μg | 50μg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $329.90 | |
| rp152513-100μg | 100μg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $539.90 | |
| rp152513-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,999.90 |
Animal Free, >97%(SDS-PAGE, HPLC), Active, E.coli, No tag, 22-211 aa
| Product Name | Recombinant Human TNFRSF1A Protein, ＞97%(SDS-PAGE, HPLC), high purity |
|---|---|
| Synonyms | CD120a antigen | CD120a | FPF | p55 | p55-R | p60 | TNF RI | TNFARMGC19588 | TNF-R | TNF-R1 | TNFR1TBP1 | TNFR55 | TNF-R55 | TNFR60 | TNFRI | TNF-RI | TNF-R-I | TNFR-I | TNFRSF1A | tumor necrosis factor binding protein 1 | Tumor necrosis factor receptor 1 |
| Grade | ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, High Performance |
| Product Description | Purity > 97 % by SDS-PAGE and HPLC analyses. Function Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
| Specifications & Purity | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥97%(SDS-PAGE&HPLC) |
| Purity | ＞97%(SDS-PAGE, HPLC) |
| Bioactivity | Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha. |
| Endotoxin Concentration | <0.1 EU/μg |
| Expression System | E.coli |
| Species | Human |
| Amino Acids | 22-211 aa |
| Sequence | IYPSGVIGLV PHLGDREKRD SVCPQGKYIH PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC TKLCLPQIEN VKGTEDSGTT |
| Protein Tag | No tag |
| Accession # | P19438 |
| Predicted molecular weight | 21.2 kDa |
Recombinant Human TNFRSF1A Protein (rp152513)-Protein Bioactivity
Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/mL, corresponding to a specific activity of > 2 × 104 IU/mg in the presence of 0.25 ng/mL of rHuTNF-alpha.
Recombinant Human TNFRSF1A Protein (rp152513)-SDS-PAGE
Recombinant Human TNFRSF1A Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining. Showing a single band at 21.2 kDa under reducing conditions and 19.0 kDa under non-reducing conditions.
| Form | Lyophilized |
|---|---|
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportio |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 ℃ as supplied. - 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. - 3 months, -20 to -70 ℃ under sterile conditions after reco |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F0600347 | Certificate of Analysis | Mar 26, 2024 | rp152513 |
| ZJ23F0600348 | Certificate of Analysis | Mar 26, 2024 | rp152513 |
| ZJ23F0600349 | Certificate of Analysis | Mar 26, 2024 | rp152513 |
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