Recombinant Human Uteroglobin Protein, >98%(SDS-PAGE and HPLC), high purity

Features and benefits
  • Expression System: E.coli
  • Accession #: P11684
  • Protein Tag: No tag
  • Bioactivity: Fully biologically active when compared to standard. The ED₅₀ as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 μg/ml, corresponding to a specific activity of > 200 IU/m
  • Endotoxin Concentration: <0.1 EU/μg
Item Number
rp153061
Grouped product items
SKUSizeAvailabilityPrice Qty
rp153061-10μg
10μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$89.90
rp153061-50μg
50μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$259.90
rp153061-100μg
100μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$389.90
rp153061-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,199.90

Animal Free, >98%(SDS-PAGE and HPLC), Active, E.coli, No tag, 22-91 aa

Basic Description

Product NameRecombinant Human Uteroglobin Protein, >98%(SDS-PAGE and HPLC), high purity
SynonymsBlastokinin | CC10 | CC16 | CCPBP | CCSP | Clara cell phospholipid binding protein | Clara cell phospholipid-binding protein | Clara cell specific 10 kD protein | Clara cells 10 kDa secretory protein | OTTHUMP00000236107 | SCGB1A1 | Secretoglobin family 1
GradeActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, High Performance
Product Description

Purity

>98% by SDS-PAGE  and HPLC analyses.


Function

Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

Specifications & PurityActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥98%(SDS-PAGE&HPLC)
Purity>98%(SDS-PAGE and HPLC)
BioactivityFully biologically active when compared to standard. The ED₅₀ as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 μg/ml, corresponding to a specific activity of > 200 IU/m
Endotoxin Concentration<0.1 EU/μg
Expression SystemE.coli
SpeciesHuman
Amino Acids22-91 aa
SequenceEICPSFQRVI ETLLMDTPSS YEAAMELFSP DQDMREAGAQ LKKLVDTLPQ KPRESIIKLM EKIAQSSLCN
Protein TagNo tag
Accession #P11684
Predicted molecular weight15.8 kDa

Images

Recombinant Human Uteroglobin Protein (rp153061)-Protein Bioactivity
Fully biologically active when compared to standard. The ED₅₀ as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 μg/mL, corresponding to a specific activity of > 200 IU/mg.

Recombinant Human Uteroglobin Protein (rp153061)-SDS-PAGE
Recombinant Human Uteroglobin Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 8.0 kDa under reducing conditions and 13.8 kDa under non-reducing conditions.

Product Specifications

FormLyophilized
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportio
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconst

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ23F0600500Certificate of AnalysisMar 26, 2024 rp153061
ZJ23F0600501Certificate of AnalysisMar 26, 2024 rp153061
ZJ23F0600502Certificate of AnalysisMar 26, 2024 rp153061

Related Documents

References

1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K et al..  (2004)  Complete sequencing and characterization of 21,243 full-length human cDNAs..  Nat Genet,  36  (1): (40-5).  [PMID:14702039] [10.1021/op500134e]
2. Wolf, M M and 6 more authors..  (1992)  Human CC10, the homologue of rabbit uteroglobin: genomic cloning, chromosomal localization and expression in endometrial cell lines..  Human molecular genetics,      [PMID:1284526]
3. Bernard, A A and 7 more authors..  (1992)  Human urinary protein 1: evidence for identity with the Clara cell protein and occurrence in respiratory tract and urogenital secretions..  Clinica chimica acta; international journal of clinical chemistry,    (15):   [PMID:1395029]
4. Singh, G G and 6 more authors..  (1988)  Amino-acid and cDNA nucleotide sequences of human Clara cell 10 kDa protein..  Biochimica et biophysica acta,    (7):   [PMID:3167058]
5. Umland, T C TC and 6 more authors..  (1994)  Structure of a human Clara cell phospholipid-binding protein-ligand complex at 1.9 A resolution..  Nature structural biology,      [PMID:7664082]
6. Hay, J G JG, Danel, C C, Chu, C S CS and Crystal, R G RG..  (1995)  Human CC10 gene expression in airway epithelium and subchromosomal locus suggest linkage to airway disease..  The American journal of physiology,      [PMID:7733299]
7. Ghafouri, Bijar B, Ståhlbom, Bengt B, Tagesson, Christer C and Lindahl, Mats M..  (2002)  Newly identified proteins in human nasal lavage fluid from non-smokers and smokers using two-dimensional gel electrophoresis and peptide mass fingerprinting..  Proteomics,      [PMID:11788998]
8. Zhang, Zhongjian Z and 7 more authors..  (2006)  Interaction of uteroglobin with lipocalin-1 receptor suppresses cancer cell motility and invasion..  Gene,    (15):   [PMID:16423471]
9. Hesselink, Renske W RW and Findlay, John B C JB..  ()  Expression, characterization and ligand specificity of lipocalin-1 interacting membrane receptor (LIMR)..  Molecular membrane biology,      [PMID:23964685]

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