Skip to the beginning of the images gallery

Recombinant IL-17RA Receptor Antibody - Primary antibody, specific to IL17RA, Rabbit IgG

ExactAb™
Recombinant
Validated
0.32 mg/mL

Features and benefits

Short Overview:
Recombinant; Rabbit anti Human IL-17RA Receptor Antibody; WB; Unconjugated
Species reactivity(Reacts with): Human
Isotype: Rabbit IgG

Application:

Item Number

Ab109992

Grouped product items
SKU	Size	Availability	Price
Ab109992-10μl	10μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90
Ab109992-50μl	50μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90
Ab109992-100μl	100μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$309.90
Ab109992-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,699.90

Recombinant; Rabbit anti Human IL-17RA Receptor Antibody; WB; Unconjugated

View related series

Accession#:Q96F46 Gene ID:23765 IL17RA

Basic Description

Product Name	Recombinant IL-17RA Receptor Antibody - Primary antibody, specific to IL17RA, Rabbit IgG
Synonyms	CDw217 \| IL-17 receptor A \| IL-17RA \| CANDF5 antibody \| CD217 antibody \| CD217 antigen antibody \| CDw217 antibody \| CTLA8 antibody \| HIL 17R antibody \| hIL17R antibody \| I17RA_HUMAN antibody \| IL 17 receptor A antibody \| IL 17 receptor antibody \| IL 17RA
Specifications & Purity	ExactAb™, Validated, Recombinant, 0.32 mg/mL
Host species	Rabbit
Specificity	IL17RA
Immunogen	A synthetic peptide derived from human IL17A Receptor (AA 801-866)
Positive Control	WB: Jurkat and K562 cell lysates.
Conjugation	Unconjugated
Grade	ExactAb™, Recombinant, Validated
Product Description	Rabbit anti Human IL-17RA Receptor Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. Post-translational Glycosylated.

Product Properties

Isotype	Rabbit IgG
Light Chain Type	kappa
SDS-PAGE	150 kDa
Purification Method	Protein A purified
Form	Liquid
Concentration	0.32 mg/mL
Storage Temp	Store at -20°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Application

Dilution info

1/500-1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0708984	Certificate of Analysis	Jul 31, 2024	Ab109992
ZJ24F0708983	Certificate of Analysis	Jul 31, 2024	Ab109992

References

1. Wright JF, Bennett F, Li B, Brooks J, Luxenberg DP, Whitters MJ, Tomkinson KN, Fitz LJ, Wolfman NM, Collins M et al.. (2008) The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex.. J Immunol, 181 (4): (2799-805). [PMID:18684971]
2. Ramirez-Carrozzi V, Sambandam A, Luis E, Lin Z, Jeet S, Lesch J, Hackney J, Kim J, Zhou M, Lai J et al.. (2011) IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.. Nat Immunol, 12 (12): (1159-66). [PMID:21993848]
3. Yao, Z Z and 8 more authors.. (1997) Molecular characterization of the human interleukin (IL)-17 receptor.. Cytokine, [PMID:9367539]
4. Zhang, Zemin Z and Henzel, William J WJ.. (2004) Signal peptide prediction based on analysis of experimentally verified cleavage sites.. Protein science : a publication of the Protein Society, [PMID:15340161]
5. Collins, John E JE and 12 more authors.. (2004) A genome annotation-driven approach to cloning the human ORFeome.. Genome biology, [PMID:15461802]
6. Toy, Dean D and 7 more authors.. (2006) Cutting edge: interleukin 17 signals through a heteromeric receptor complex.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:16785495]
7. Kuestner, Rolf E RE and 27 more authors.. (2007) Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:17911633]
8. Ely, Lauren K LK, Fischer, Suzanne S and Garcia, K Christopher KC.. (2009) Structural basis of receptor sharing by interleukin 17 cytokines.. Nature immunology, [PMID:19838198]
9. Puel, Anne A and 23 more authors.. (2011) Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity.. Science (New York, N.Y.), (1): [PMID:21350122]
10. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163]
11. Sohda, Miwa M and 5 more authors.. (2013) Identification of a soluble isoform of human IL-17RA generated by alternative splicing.. Cytokine, [PMID:24084331]
12. Boisson, Bertrand B and 12 more authors.. (2013) An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.. Immunity, (17): [PMID:24120361]
13. Goepfert, Arnaud A, Lehmann, Sylvie S, Wirth, Emmanuelle E and Rondeau, Jean-Michel JM.. (2017) The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties.. Scientific reports, (21): [PMID:28827714]
14. Goepfert, Arnaud; Lehmann, Sylvie; Blank, Jutta; Kolbinger, Frank and Rondeau, Jean-Michel.. (2020) Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling.. Immunity, (17): [PMID:32187518]
15. Gordon, David E and 199 more authors.. (2020) Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.. Science (New York, N.Y.), (4): [PMID:33060197]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.