Click Here for 5% Off Your First Aladdin Purchase!

Recombinant Integrin beta 3 Antibody - Primary antibody, specific to Integrin beta 3, Mouse IgG1

  • ExactAb™
  • Recombinant
  • Validated
  • 0.04 mg/mL
Features and benefits
  • Short Overview:

    Recombinant (MyM1-CD61); Mouse anti Human Integrin beta 3 Antibody; IHC; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG1
    Application:
  • IHC
Item Number
Ab110871
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab110871-10μl
10μl
In stock
$69.90
Ab110871-50μl
50μl
In stock
$199.90
Ab110871-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab110871-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,499.90

Recombinant (MyM1-CD61); Mouse anti Human Integrin beta 3 Antibody; IHC; Unconjugated

Basic Description

Product NameRecombinant Integrin beta 3 Antibody - Primary antibody, specific to Integrin beta 3, Mouse IgG1
Specifications & PurityExactAb™, Validated, Recombinant, 0.04 mg/mL
Host speciesMouse
SpecificityIntegrin beta 3
Positive ControlIHC: Human spleen tissue.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Mouse anti Human Integrin beta 3 Antibody, Recombinant (MyM1-CD61), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Protein Function
Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Product Properties

IsotypeMouse IgG1
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.04 mg/mL
Storage TempStore at 2-8°C,Freeze prohibited
Shipped InWet ice
Stability And StorageStore at 2-8°C long term (36 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Integrin beta 3 Antibody (Ab110871) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling Integrin beta 3 with Recombinant Integrin beta 3 Antibody (Ab110871) at 1/100 dilution. The section was incubated with Ab110871 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Associated Targets

ITGB3 Tclin Integrin beta-3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IHC

1/100 - 1/200

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0505254Certificate of AnalysisMay 09, 2024 Ab110871
ZJ24F0505253Certificate of AnalysisMay 09, 2024 Ab110871

Related Documents

Solution Calculators