Recombinant; Rabbit anti Human ITGB6 Antibody; WB; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab111364-10μl | 10μl | In stock | $69.90 | |
| Ab111364-50μl | 50μl | In stock | $209.90 | |
| Ab111364-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $339.90 | |
| Ab111364-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,299.90 |
Recombinant; Rabbit anti Human ITGB6 Antibody; WB; Unconjugated
| Product Name | Recombinant ITGB6 Antibody - Primary antibody, specific to ITGB6, Rabbit IgG |
|---|---|
| Synonyms | Integrin beta-6 antibody; ITB6_HUMAN antibody; ITGB6 antibody; Integrin beta 6; integrin beta-6; integrin, beta 6; ITGB6 |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.4 mg/mL |
| Host species | Rabbit |
| Specificity | ITGB6 |
| Immunogen | A synthetic peptide derived from human ITGB6 (AA 121-134). |
| Positive Control | WB: C6, NIH/3T3, HEK293, A549 and HeLa cell lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human ITGB6 Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Antigen affinity purified |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant ITGB6 Antibody (Ab111364) - Western Blot
All lanes: Recombinant ITGB6 Antibody (Ab111364) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 86 kDa
Observed band size: 87 kDa
Exposure time: 4.1 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB |
1/500-1/1000
|
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0202756 | Certificate of Analysis | Feb 06, 2024 | Ab111364 |
| ZJ24F0202755 | Certificate of Analysis | Feb 06, 2024 | Ab111364 |
| 1. Anderson NA, Campos S, Butler S, Copley RCB, Duncan I, Harrison S, Le J, Maghames R, Pastor-Garcia A, Pritchard JM et al.. (2019) Discovery of an Orally Bioavailable Pan αv Integrin Inhibitor for Idiopathic Pulmonary Fibrosis.. J Med Chem, 62 (19): (8796-8808). [PMID:31497959] |
| 2. Jiang, W M WM and 6 more authors.. (1992) The gene organization of the human beta 7 subunit, the common beta subunit of the leukocyte integrins HML-1 and LPAM-1.. International immunology, [PMID:1382574] |
| 3. Sheppard, D D and 5 more authors.. (1990) Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.. The Journal of biological chemistry, (15): [PMID:2365683] |
| 4. Agrez, M V MV and 5 more authors.. (1997) Integrin alpha v beta 6 enhances coxsackievirus B1 lytic infection of human colon cancer cells.. Virology, (8): [PMID:9426447] |
| 5. van der Flier, Arjan A and 7 more authors.. (2002) Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.. The Journal of cell biology, (21): [PMID:11807098] |
| 6. Annes, Justin P; Chen, Yan; Munger, John S and Rifkin, Daniel B.. (2004) Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1.. The Journal of cell biology, (7): [PMID:15184403] |
| 7. Williams, Ciğdem H CH and 5 more authors.. (2004) Integrin alpha v beta 6 is an RGD-dependent receptor for coxsackievirus A9.. Journal of virology, [PMID:15194773] |
| 8. Hillier, Ladeana W LW and 121 more authors.. (2005) Generation and annotation of the DNA sequences of human chromosomes 2 and 4.. Nature, (7): [PMID:15815621] |
| 9. Jovanovic, Jelena J and 7 more authors.. (2007) alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity.. The Journal of biological chemistry, (2): [PMID:17158881] |
| 10. Wang, Rui R and 5 more authors.. (2012) GARP regulates the bioavailability and activation of TGFβ.. Molecular biology of the cell, [PMID:22278742] |
| 11. Wang, Shih-Kai SK and 8 more authors.. (2014) ITGB6 loss-of-function mutations cause autosomal recessive amelogenesis imperfecta.. Human molecular genetics, (15): [PMID:24305999] |
| 12. Poulter, James A JA and 7 more authors.. (2014) A missense mutation in ITGB6 causes pitted hypomineralized amelogenesis imperfecta.. Human molecular genetics, (15): [PMID:24319098] |
| 13. Gianni, Tatiana T, Salvioli, Stefano S, Chesnokova, Liudmila S LS, Hutt-Fletcher, Lindsey M LM and Campadelli-Fiume, Gabriella G.. (2013) αvβ6- and αvβ8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion.. PLoS pathogens, [PMID:24367260] |
| 14. Dong, Xianchi X and 7 more authors.. (2017) Force interacts with macromolecular structure in activation of TGF-β.. Nature, (2): [PMID:28117447] |
