Recombinant; Rabbit anti Human KAT1/HAT1 Antibody; WB, IHC; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab111737-10μl | 10μl | In stock | $69.90 | |
| Ab111737-50μl | 50μl | In stock | $199.90 | |
| Ab111737-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $299.90 | |
| Ab111737-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,799.90 |
Recombinant; Rabbit anti Human KAT1/HAT1 Antibody; WB, IHC; Unconjugated
| Product Name | Recombinant KAT1/HAT1 Antibody - Primary antibody, specific to KAT1/HAT1, Rabbit IgG |
|---|---|
| Synonyms | HAT 1 antibody; hat1 antibody; HAT1_HUMAN antibody; Histidine aminotransferase 1 antibody; Histone acetyltransferase 1antibody; Histone acetyltransferase 1 antibody; Histone acetyltransferase type B catalytic subunit antibody; KAT1 antibody |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 1.0 mg/mL |
| Host species | Rabbit |
| Specificity | KAT1/HAT1 |
| Immunogen | Recombinant protein of human KAT1/HAT1 (AA 2-200) |
| Positive Control | WB: HeLa, K562, Jurkat, U2OS, MCF7, NIH/3T3 and C6 cell lysates. IHC: Human tonsil tissue. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human KAT1/HAT1 Antibody, Recombinant, could be used for WB, IHC and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Antigen affinity purified |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant KAT1/HAT1 Antibody (Ab111737) - Western Blot
All lanes: Recombinant KAT1/HAT1 Antibody (Ab111737) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 50 kDa
Observed band size: 47 kDa
Exposure time: 5.9 s
Recombinant KAT1/HAT1 Antibody (Ab111737) - Western Blot
All lanes: Recombinant KAT1/HAT1 Antibody (Ab111737) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 50 kDa
Observed band size: 47 kDa
Exposure time: 27.8 s
Recombinant KAT1/HAT1 Antibody (Ab111737) - IHC
Immunohistochemistry analysis of paraffin-embedded Human tonsil using Recombinant KAT1/HAT1 Antibody (Ab111737). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50 - 1/100 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0303891 | Certificate of Analysis | Apr 02, 2024 | Ab111737 |
| ZJ24F0303890 | Certificate of Analysis | Apr 02, 2024 | Ab111737 |
| 1. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed. (2009-05-06) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.. Analytical chemistry, 81 ((11)): (4493-4501). [PMID:19413330] |
| 2. Pan S,Zhou Y,Wang Q,Wang Y,Tian C,Wang T,Huang L,Nan J,Li L,Yang S. (2020) Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO).. Eur J Med Chem, 207 (112703-112703). [PMID:32871341] |
| 3. Verreault, A A, Kaufman, P D PD, Kobayashi, R R and Stillman, B B.. (1998) Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase.. Current biology : CB, (15): [PMID:9427644] |
| 4. Makowski, A M AM, Dutnall, R N RN and Annunziato, A T AT.. (2001) Effects of acetylation of histone H4 at lysines 8 and 16 on activity of the Hat1 histone acetyltransferase.. The Journal of biological chemistry, (23): [PMID:11585814] |
| 5. Sorbello, V V and 8 more authors.. () Quantitative real-time RT-PCR analysis of eight novel estrogen-regulated genes in breast cancer.. The International journal of biological markers, [PMID:12841681] |
| 6. Hillier, Ladeana W LW and 121 more authors.. (2005) Generation and annotation of the DNA sequences of human chromosomes 2 and 4.. Nature, (7): [PMID:15815621] |
| 7. Sjöblom, Tobias T and 28 more authors.. (2006) The consensus coding sequences of human breast and colorectal cancers.. Science (New York, N.Y.), (13): [PMID:16959974] |
| 8. Bienvenut, Willy V WV and 6 more authors.. (2012) Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features.. Molecular & cellular proteomics : MCP, [PMID:22223895] |
| 9. Wu, Hong H and 6 more authors.. (2012) Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1.. Proceedings of the National Academy of Sciences of the United States of America, (5): [PMID:22615379] |
| 10. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 11. Yang, Xiaohan X and 9 more authors.. (2013) Histone acetyltransferase 1 promotes homologous recombination in DNA repair by facilitating histone turnover.. The Journal of biological chemistry, (21): [PMID:23653357] |
| 12. Marin, Traci L TL and 9 more authors.. (2017) AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1.. Science signaling, (31): [PMID:28143904] |
| 13. Gruber, Joshua J JJ and 8 more authors.. (2019) HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding.. Molecular cell, (22): [PMID:31278053] |
| 14. Yang, Guang and 16 more authors.. (2019) HAT1 signaling confers to assembly and epigenetic regulation of HBV cccDNA minichromosome.. Theranostics, [PMID:31695772] |
