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Recombinant MBNL1 Antibody - Primary antibody, specific to MBNL1, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 0.2 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human MBNL1 Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab114435
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab114435-10μl
10μl
In stock
$69.90
Ab114435-50μl
50μl
In stock
$199.90
Ab114435-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab114435-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,619.90

Recombinant; Rabbit anti Human MBNL1 Antibody; WB; Unconjugated

View related series
Accession#:Q9NR56 Gene ID:4154 MBNL1

Basic Description

Product NameRecombinant MBNL1 Antibody - Primary antibody, specific to MBNL1, Rabbit IgG
SynonymsEXP | MBNL | EXP antibody | EXP35 antibody | EXP40 antibody | EXP42 antibody | KIAA0428 antibody | MBNL antibody | MBNL protein antibody | MBNL1 antibody | MBNL1_HUMAN antibody | Muscleblind 41kD isoform antibody | Muscleblind like antibody | Muscleblind
Specifications & PurityExactAb™, Validated, Recombinant, 0.2 mg/mL
Host speciesRabbit
SpecificityMBNL1
ImmunogenA synthetic peptide derived from human MBNL1 (AA 377-387)
Positive ControlWB: Jurkat and HeLa cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human MBNL1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function:
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen Affinity purified
FormLiquid
Concentration0.2 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant MBNL1 Antibody (Ab114435) - Western Blot
All lanes: Recombinant MBNL1 Antibody (Ab114435) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 42 kDa
Observed band size: 39, 42 kDa
Exposure time: 64.0 s

Associated Targets

MBNL1 Tbio Muscleblind-like protein 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303393Certificate of AnalysisMar 20, 2024 Ab114435
ZJ24F0303392Certificate of AnalysisMar 20, 2024 Ab114435

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