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Recombinant NDEL1 Antibody

  • ExactAb™
  • KD验证
  • Recombinant
  • Validated
  • Lot by Lot
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human NDEL1 Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab117292
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab117292-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab117292-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab117292-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$369.90
Ab117292-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,499.90

Recombinant; Rabbit anti Human NDEL1 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant NDEL1 Antibody
Specifications & PurityRecombinant, Validated, ExactAb™, KD, Lot by Lot
Host speciesRabbit
SpecificityNDEL1
ImmunogenA synthetic peptide derived from human NUDEL (AA 1-36)
Positive ControlWB: HeLa, Jurkat, HEK293, A549, RAW 264.7 and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, KD验证, Recombinant, Validated
Product Description

Rabbit anti Human NDEL1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/2000 
Protein Function:
Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant NDEL1 Antibody (Ab117292) - Western Blot
All lanes: Recombinant NDEL1 Antibody (Ab117292) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 40 kDa
Observed band size: 42 kDa
Exposure time: 60.0 s

Associated Targets

NDEL1 Tbio Nuclear distribution protein nudE-like 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/2000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Solution Calculators