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Recombinant NEDD4-2 Antibody

  • ExactAb™
  • High performance
  • Recombinant
  • Validated
  • Lot by Lot
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human NEDD4-2 Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab117486
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab117486-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab117486-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab117486-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab117486-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human NEDD4-2 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant NEDD4-2 Antibody
Specifications & PurityExactAb™, Validated, Recombinant, High performance, Lot by Lot
Host speciesRabbit
SpecificityNEDD4L
ImmunogenA synthetic peptide derived from human NEDD4-2 (AA 920-975)
Positive ControlWB: K562, HeLa, HepG2, Jurkat, MCF-7 lysates.
ConjugationUnconjugated
GradeExactAb™, High performance, Recombinant, Validated
Product Description

Rabbit anti Human NEDD4-2 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/5000-1/20000
Protein Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Associated Targets

NEDD4L Tbio E3 ubiquitin-protein ligase NEDD4-like 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/5000-1/20000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Solution Calculators