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Recombinant PSMB8/LMP7 Antibody - Primary antibody, specific to PSMB8/LMP7, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 1.0 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human PSMB8/LMP7 Antibody; WB, ICC, IF; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse
  • Isotype: Rabbit IgG
    Application:
  • IF/ICC
  • WB
Item Number
Ab123408
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab123408-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab123408-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab123408-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$319.90
Ab123408-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

Recombinant; Rabbit anti Human PSMB8/LMP7 Antibody; WB, ICC, IF; Unconjugated

Basic Description

Product NameRecombinant PSMB8/LMP7 Antibody - Primary antibody, specific to PSMB8/LMP7, Rabbit IgG
Specifications & PurityExactAb™, Validated, Recombinant, 1.0 mg/mL
Host speciesRabbit
SpecificityPSMB8/LMP7
ImmunogenA synthetic peptide derived from human LMP7 (AA 212-225)
Positive ControlWB: HeLa, Raji, Ramos and U937 cell lysates. ICC/IF: HeLa cells.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human PSMB8/LMP7 Antibody, Recombinant, could be used for WB, ICC, IF and so on.
Application:
WB: 1/500-1/1000
ICC/IF: 1/50-1/200
Protein Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells, substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen affinity purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant PSMB8/LMP7 Antibody (Ab123408) - Western Blot
All lanes: Recombinant PSMB8/LMP7 Antibody (Ab123408) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 30 kDa
Observed band size: 25 kDa
Exposure time: 50.0 s

Recombinant PSMB8/LMP7 Antibody (Ab123408) - IF/ICC
Immunocytochemistry analysis of LMP7 (green) in HeLa using Recombinant PSMB8/LMP7 Antibody (Ab123408) and DAPI (blue). 

Application

ApplicationDilution info
ICC/IF

1/50-1/200

WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Solution Calculators