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Recombinant RRP42 Antibody - Primary antibody, specific to EXOSC7, Rabbit IgG

ExactAb™
Recombinant
Validated
0.33 mg/mL

Features and benefits

Short Overview:
Recombinant; Rabbit anti Human RRP42 Antibody; WB; Unconjugated
Species reactivity(Reacts with): Human
Isotype: Rabbit IgG

Application:

Item Number

Ab126030

Grouped product items
SKU	Size	Availability	Price
Ab126030-10μl	10μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$79.90
Ab126030-50μl	50μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$229.90
Ab126030-100μl	100μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$379.90
Ab126030-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,999.90

Recombinant; Rabbit anti Human RRP42 Antibody; WB; Unconjugated

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Basic Description

Product Name	Recombinant RRP42 Antibody - Primary antibody, specific to EXOSC7, Rabbit IgG
Specifications & Purity	ExactAb™, Validated, Recombinant, 0.33 mg/mL
Host species	Rabbit
Specificity	EXOSC7
Immunogen	A synthetic peptide derived from human EXOSC7 (AA 250-291)
Positive Control	WB: Jurkat, K562, Hep G2, A431 and HeLa cell lysates.
Conjugation	Unconjugated
Grade	ExactAb™, Recombinant, Validated
Product Description	Rabbit anti Human RRP42 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function: Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as anti-sense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.

Product Properties

Isotype	Rabbit IgG
Light Chain Type	kappa
SDS-PAGE	150 kDa
Purification Method	Protein A purified
Form	Liquid
Concentration	0.33 mg/mL
Storage Temp	Store at -20°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant RRP42 Antibody (Ab126030) - Western Blot
All lanes: Recombinant RRP42 Antibody (Ab126030) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 32 kDa
Observed band size: 34 kDa
Exposure time: 1.5 s

Application

Dilution info

1/500-1/2000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0708243	Certificate of Analysis	Jul 12, 2024	Ab126030
ZJ24F0708242	Certificate of Analysis	Jul 12, 2024	Ab126030

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