Recombinant SYVN1/HRD1 Antibody

Features and benefits

Short Overview:
Recombinant; Rabbit anti Human SYVN1/HRD1 Antibody; WB, IP; Unconjugated
Species reactivity(Reacts with): Human,Mouse,Rat
Isotype: Rabbit IgG

Application:

Item Number

Ab130086

Grouped product items
SKU	Size	Availability	Price
Ab130086-10μl	10μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90
Ab130086-50μl	50μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90
Ab130086-100μl	100μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$319.90
Ab130086-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,099.90

Recombinant; Rabbit anti Human SYVN1/HRD1 Antibody; WB, IP; Unconjugated

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Basic Description

Product Name	Recombinant SYVN1/HRD1 Antibody
Specifications & Purity	ExactAb™, Validated, Recombinant, Lot by Lot
Host species	Rabbit
Specificity	SYVN1/HRD1
Immunogen	A synthetic peptide derived from human SYVN1/HRD1 (AA 175-236).
Positive Control	WB: HeLa, Jurkat, HepG2, MCF-7 lysates. IP: HeLa lysates.
Conjugation	Unconjugated
Grade	ExactAb™, Recombinant, Validated
Product Description	Rabbit anti Human SYVN1/HRD1 Antibody, Recombinant, could be used for WB, IP and so on. Application: WB: 1/500-1/2000 IP: 1/50 Protein Function： Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins such as SGK. Protects cells from ER stress-induced apoptosis. Protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. Sequesters p53/TP53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis.

Product Properties

Isotype	Rabbit IgG
Light Chain Type	kappa
SDS-PAGE	150 kDa
Purification Method	Protein A purified
Form	Liquid
Concentration	Lot by Lot
Storage Temp	Store at -20°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Application

Dilution info

1/50

1/500-1/2000

Solution Calculators

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Basic Description