Recombinant; Rabbit anti Human TORC2 Antibody; WB, IHC Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab132016-10μl | 10μl | In stock | $66.90 | |
| Ab132016-50μl | 50μl | In stock | $199.90 | |
| Ab132016-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $279.90 | |
| Ab132016-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,699.90 |
Recombinant; Rabbit anti Human TORC2 Antibody; WB, IHC Unconjugated
| Product Name | Recombinant TORC2 Antibody - Primary antibody, specific to CRTC2, Rabbit IgG |
|---|---|
| Synonyms | CREB regulated transcription coactivator 2; CREB-regulated transcription coactivator 2; CRTC2; TORC2; TORC-2; TORC2transducer of regulated cAMP response element-binding protein (CREB) 2; Transducer of CREB protein 2; Transducer of regulated cAMP response |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.7 mg/mL |
| Host species | Rabbit |
| Specificity | CRTC2 |
| Immunogen | A synthetic peptide derived from human TORC2 (AA 680-693). |
| Positive Control | WB: Jurkat, Raji, HEK293, NIH/3T3 and C6 cell lysates. IHC：Human breast cancer tissue. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human TORC2 Antibody, Recombinant, could be used for WB, IHC and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Immunogen affinity purified |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant TORC2 Antibody (Ab132016) - Western Blot
All lanes: Recombinant TORC2 Antibody (Ab132016) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 73 kDa
Observed band size: 81 kDa
Exposure time: 13.3 s
Recombinant TORC2 Antibody (Ab132016) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Recombinant TORC2 Antibody (Ab132016). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/50 - 1/100 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0202860 | Certificate of Analysis | Feb 23, 2024 | Ab132016 |
| ZJ24F0202859 | Certificate of Analysis | Feb 23, 2024 | Ab132016 |
| 1. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed. (2009-05-06) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.. Analytical chemistry, 81 ((11)): (4493-4501). [PMID:19413330] |
| 2. Iourgenko, Vadim V and 20 more authors.. (2003) Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.. Proceedings of the National Academy of Sciences of the United States of America, (14): [PMID:14506290] |
| 3. Conkright, Michael D MD and 6 more authors.. (2003) TORCs: transducers of regulated CREB activity.. Molecular cell, [PMID:14536081] |
| 4. Screaton, Robert A RA and 11 more authors.. (2004) The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.. Cell, (1): [PMID:15454081] |
| 5. Bittinger, Mark A MA and 9 more authors.. (2004) Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins.. Current biology : CB, (14): [PMID:15589160] |
| 6. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414] |
| 7. Siu, Yeung-Tung YT and 5 more authors.. (2006) TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeats.. Journal of virology, [PMID:16809310] |
| 8. Katoh, Yoshiko Y and 12 more authors.. (2006) Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade.. The FEBS journal, [PMID:16817901] |
| 9. Beausoleil, Sean A SA, Villén, Judit J, Gerber, Scott A SA, Rush, John J and Gygi, Steven P SP.. (2006) A probability-based approach for high-throughput protein phosphorylation analysis and site localization.. Nature biotechnology, [PMID:16964243] |
| 10. Wu, Zhidan Z and 9 more authors.. (2006) Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.. Proceedings of the National Academy of Sciences of the United States of America, (26): [PMID:16980408] |
| 11. Keshavarz, Parvaneh P and 5 more authors.. (2008) Single nucleotide polymorphisms in genes encoding LKB1 (STK11), TORC2 (CRTC2) and AMPK alpha2-subunit (PRKAA2) and risk of type 2 diabetes.. Molecular genetics and metabolism, [PMID:17950019] |
| 12. Jansson, Deidre D and 5 more authors.. (2008) Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2.. Proceedings of the National Academy of Sciences of the United States of America, (22): [PMID:18626018] |
| 13. Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18): [PMID:19690332] |
| 14. Rigbolt, Kristoffer T G KT and 9 more authors.. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.. Science signaling, (15): [PMID:21406692] |
| 15. Van Damme, Petra P and 15 more authors.. (2012) N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.. Proceedings of the National Academy of Sciences of the United States of America, (31): [PMID:22814378] |
| 16. Sonntag, Tim T and 6 more authors.. (2019) Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment.. iScience, (25): [PMID:30611118] |
