Recombinant UQCRC2 Antibody - Primary antibody, specific to UQCRC2, Rabbit IgG
Synonyms
Ubiquinol cytochrome c reductase complex core protein 2 mitochondrial | Ubiquinol cytochrome c reductase core protein II | UQCRC2 | EC 1.10.2.2 | Complex III subunit 2 antibody | Core protein II antibody | Cytochrome b c1 complex subunit 2 mitochondrial a
Specifications & Purity
ExactAb™, Validated, Recombinant, 1.0 mg/mL
Host species
Rabbit
Specificity
UQCRC2
Immunogen
A synthetic peptide derived from human UQCRC2 (AA 300-375)
Positive Control
WB: HEK293, U2OS, Hep G2 and Jurkat cell lysates.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Rabbit anti Human UQCRC2 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
Product Properties
Isotype
Rabbit IgG
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
1.0 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant UQCRC2 Antibody (Ab133585) - Western Blot All lanes: Recombinant UQCRC2 Antibody (Ab133585) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 48 kDa Observed band size: 43 kDa Exposure time: 2.0 s
1.Hosokawa, Y Y, Suzuki, H H, Toda, H H, Nishikimi, M M and Ozawa, T T.. (1989) Complementary DNA encoding core protein II of human mitochondrial cytochrome bc1 complex. Substantial diversity in deduced primary structure from its yeast counterpart.. The Journal of biological chemistry, (15):[PMID:2547763]
2.Sjöblom, Tobias T and 28 more authors.. (2006) The consensus coding sequences of human breast and colorectal cancers.. Science (New York, N.Y.), (13):[PMID:16959974]
3.Miyake, Noriko N and 17 more authors.. (2013) Mitochondrial complex III deficiency caused by a homozygous UQCRC2 mutation presenting with neonatal-onset recurrent metabolic decompensation.. Human mutation, [PMID:23281071]
4.Fernandez-Vizarra, Erika E and Zeviani, Massimo M.. (2018) Mitochondrial complex III Rieske Fe-S protein processing and assembly.. Cell cycle (Georgetown, Tex.), [PMID:29243944]
5.Moutaoufik, Mohamed Taha and 27 more authors.. (2019) Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.. iScience, (27):[PMID:31536960]
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