RET-IN-3 - 99%, high purity , CAS No.2414374-53-9

Item Number

R647422

Grouped product items
SKU	Size	Availability	Price
R647422-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
R647422-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$580.90
R647422-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,100.90
R647422-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,700.90
R647422-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,500.90

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Basic Description

Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC 50 of 19 nM.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC 50 of 19 nM In Vitro RET-IN-3 exhibits 16 and 410 fold selectivity compared to wt-RET and KDR, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 19 nM (RETV804M)

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	N-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N',N'-dimethylpropane-1,3-diamine
INCHI	InChI=1S/C18H21N5O2/c1-22(2)8-3-7-19-17-6-9-23-18(21-17)14(11-20-23)13-4-5-15-16(10-13)25-12-24-15/h4-6,9-11H,3,7-8,12H2,1-2H3,(H,19,21)
InChi Key	DQYRQFLRDJTHQM-UHFFFAOYSA-N
Canonical SMILES	CN(C)CCCNC1=NC2=C(C=NN2C=C1)C3=CC4=C(C=C3)OCO4
Isomeric SMILES	CN(C)CCCNC1=NC2=C(C=NN2C=C1)C3=CC4=C(C=C3)OCO4
PubChem CID	146018674
Molecular Weight	339.4

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Basic Description