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RET-IN-3 - 10mM in DMSO, high purity , CAS No.2414374-53-9(DMSO)

  • 10mM in DMSO
Item Number
R655025
Grouped product items
SKUSizeAvailabilityPrice Qty
R655025-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$385.90
View related series
Protein Tyrosine Kinase/RTK RET

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC 50 of 19 nM

In Vitro

RET-IN-3 exhibits 16 and 410 fold selectivity compared to wt-RET and KDR, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 19 nM (RETV804M)

Associated Targets

RET Tclin Proto-oncogene tyrosine-protein kinase receptor Ret 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES CN(C)CCCNC1=NC2=C(C=NN2C=C1)C3=CC4=C(C=C3)OCO4
Molecular Weight 339.4

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators