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Retinyl acetate - for cell culture, high purity , CAS No.127-47-9

  • for cell culture
Item Number
R105893
Grouped product items
SKUSizeAvailabilityPrice Qty
R105893-1g
1g
In stock
$42.90
R105893-5g
5g
In stock
$115.90
R105893-25g
25g
In stock
$405.90
R105893-100g
100g
In stock
$1,297.90
View related series
Vitamins

Basic Description

SynonymsRETINYL ACETATE|Vitamin A acetate|Retinol acetate|127-47-9|Retinol, acetate|all-trans-Retinyl acetate|Crystalets|Vitamin A1 acetate|all-trans-Retinol acetate|Vitamin A alcohol acetate|Davitan A 650|Vitamin A ester|all-trans-Vitamin A acetate|Retinol, acet
Specifications & Purityfor cell culture
Biochemical and Physiological MechanismsThe oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cel
Storage TempProtected from light,Store at -20°C,Desiccated
Shipped InIce chest + Ice pads
Gradefor cell culture
Product Description

Retinyl-acetate is a natural and ester derivative of vitamin A. It is found in classical media formulations such as M-199; NCTC-109 and William′s Medium E. Vitamin A is a component of serum useful in most serum containing cell culture systems, which receive some level of vitamin A.


Application:

Retinyl acetate has been used as a standard to measure the concentration of vitamin C in high performance liquid chromatography analysis (HPLC) and as a supplement in the preparation of the complete medium.


Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ESR1 Tclin Estrogen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

VDR Tclin Vitamin D3 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FTL Tbio Ferritin light chain 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RXRA Tclin Retinoic acid receptor RXR-alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RGS4 Tchem Regulator of G-protein signaling 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1H4 Tclin Bile acid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1I2 Tchem Nuclear receptor subfamily 1 group I member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488190869
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488190869
IUPAC Name [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate
INCHI InChI=1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
InChi Key QGNJRVVDBSJHIZ-QHLGVNSISA-N
Canonical SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCOC(=O)C)C)C
Isomeric SMILES CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/COC(=O)C)/C)/C
WGK Germany 2
RTECS VH6825000
PubChem CID 638034
Molecular Weight 328.49
Beilstein 1915439

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

10 results found

Lot NumberCertificate TypeDateItem
G2415650Certificate of AnalysisJun 24, 2024 R105893
G2415651Certificate of AnalysisJun 24, 2024 R105893
E23171015Certificate of AnalysisDec 30, 2022 R105893
E23171020Certificate of AnalysisDec 30, 2022 R105893
E23171026Certificate of AnalysisDec 30, 2022 R105893
E23171032Certificate of AnalysisDec 30, 2022 R105893
E23171061Certificate of AnalysisDec 30, 2022 R105893
E23171097Certificate of AnalysisDec 30, 2022 R105893
E23171102Certificate of AnalysisDec 30, 2022 R105893
E23171111Certificate of AnalysisDec 30, 2022 R105893

Chemical and Physical Properties

SolubilitySoluble in Ethanol and DMSO;Slightly soluble or insoluble in water
SensitivityLight sensitive.
Refractive Index1.547-1.555
Melt Point(°C)57-58 °C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H413:May cause long lasting harmful effects to aquatic life

H302:Harmful if swallowed

Precautionary Statements

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P362+P364:Take off contaminated clothing and wash it before reuse.

P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.

WGK Germany 2
RTECS VH6825000

Related Documents

References

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