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RIPK1-IN-4 - 10mM in DMSO, high purity , CAS No.1481641-08-0(DMSO)

Item Number

R655286

Grouped product items
SKU	Size	Availability	Price	Qty
R655286-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$309.90

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Basic Description

Specifications & Purity	10mM in DMSO
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC 50 s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase IC50& Target:IC50: 16 nM (RIP1) and 10 nM (ADP-Glo)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Canonical SMILES	CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CC=CC4=C3C=CN=C4N
Molecular Weight	401.46

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