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TKL:Tyrosine kinase-like
RIPK2 inhibitor 8 , CAS No.R613201, Inhibitor of receptor interacting serine/threonine kinase 2

RIPK2 inhibitor 8 , CAS No.R613201, Inhibitor of receptor interacting serine/threonine kinase 2

Item Number

R613201

Grouped product items
SKU	Size	Availability	Price	Qty
R613201-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$356.90
R613201-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,246.90

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Basic Description

Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of receptor interacting serine/threonine kinase 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	4-[7-ethoxy-6-(2-methylpropane-2-sulfonyl)imidazo[1,2-a]pyridin-3-yl]-6-fluoropyridin-2-amine
INCHI	InChI=1S/C18H21FN4O3S/c1-5-26-13-8-17-21-9-12(11-6-15(19)22-16(20)7-11)23(17)10-14(13)27(24,25)18(2,3)4/h6-10H,5H2,1-4H3,(H2,20,22)
InChi Key	QWDMZDSZMVJFFJ-UHFFFAOYSA-N
Canonical SMILES	CCOc1cc2ncc(n2cc1S(=O)(=O)C(C)(C)C)c1cc(N)nc(c1)F
Isomeric SMILES	CCOC1=CC2=NC=C(N2C=C1S(=O)(=O)C(C)(C)C)C3=CC(=NC(=C3)F)N
PubChem CID	131801159

PubChem CID	131801159

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1. He X, Da Ros S, Nelson J, Zhu X, Jiang T, Okram B, Jiang S, Michellys PY, Iskandar M, Espinola S et al.. (2017) Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.. ACS Med Chem Lett, 8 (10): (1048-1053). [PMID:29057049]

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