RKI-1447 - ≥98%, high purity , CAS No.1342278-01-6, Inhibitor of CDC42 binding protein kinase alpha;Inhibitor of DM1 protein kinase;Inhibitor of LIM domain kinase 1;Inhibitor of myosin light chain kinase;Inhibitor of p21 (RAC1) activated kinase 1;Inhibitor of protein kinase N1;Inhibitor of Rho associated c
RKI-1447 - ≥98%, high purity , CAS No.1342278-01-6, Inhibitor of CDC42 binding protein kinase alpha;Inhibitor of DM1 protein kinase;Inhibitor of LIM domain kinase 1;Inhibitor of myosin light chain kinase;Inhibitor of p21 (RAC1) activated kinase 1;Inhibitor of protein kinase N1;Inhibitor of Rho associated c
Inhibitor of CDC42 binding protein kinase alpha;Inhibitor of DM1 protein kinase;Inhibitor of LIM domain kinase 1;Inhibitor of myosin light chain kinase;Inhibitor of p21 (RAC1) activated kinase 1;Inhibitor of protein kinase N1;Inhibitor of Rho associated c
Note
卖完停产，不再备货
Product Description
RKI-1447 is a potent inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, has anti-invasive and antitumor activities.
1.Pireddu R, Forinash KD, Sun NN, Martin MP, Sung SS, Alexander B, Zhu JY, Guida WC, Schönbrunn E, Sebti SM et al.. (2012) Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2).. Medchemcomm, 3 (6):(699-709). [PMID:23275831]
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F1503112