JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

RMM 46 - ≥98%(HPLC), high purity , CAS No.1307896-46-3

Item Number

R288282

Grouped product items
SKU	Size	Availability	Price	Qty
R288282-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$189.90
R288282-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$794.90

MSK/RSK family kinase inhibitor

Basic Description

Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	MSK/RSK family kinase inhibitor. Exhibits selectivity for RSK2 over NEK2 and PLK1 (IC50s are 12, 530 and 2200 nM, respectively). Inhibits MSK1, MSK2, RSK2 and RSK3 in cellular assays. Reduces CREB phosphorylation in HeLa cells.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

IUPAC Name	(E)-2-cyano-N-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide
INCHI	InChI=1S/C24H26N4O5/c1-24(2,13-29)26-23(30)16(12-25)8-14-6-7-18-17(9-14)21(28-27-18)15-10-19(31-3)22(33-5)20(11-15)32-4/h6-11,29H,13H2,1-5H3,(H,26,30)(H,27,28)/b16-8+
InChi Key	FCCMYBKAZCDQGX-LZYBPNLTSA-N
Canonical SMILES	CC(C)(CO)NC(=O)C(=CC1=CC2=C(C=C1)NN=C2C3=CC(=C(C(=C3)OC)OC)OC)C#N
Isomeric SMILES	CC(C)(CO)NC(=O)/C(=C/C1=CC2=C(C=C1)NN=C2C3=CC(=C(C(=C3)OC)OC)OC)/C#N
PubChem CID	67206797
Molecular Weight	450.5

Enter Lot Number to search for COA:

Solubility	Solvent:DMSO, Max Conc. mg/mL: 45.05, Max Conc. mM: 100

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.