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Ropivacaine hydrochloride monohydrate - ≥98% (HPLC), high purity , CAS No.132112-35-7

  • ≥98%(HPLC)
Item Number
R131964
Grouped product items
SKUSizeAvailabilityPrice Qty
R131964-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$48.90
R131964-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$88.90
R131964-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$400.90
R131964-1g
1g
In stock
$1,441.90
R131964-5g
5g
In stock
$6,488.90
R131964-25g
25g
In stock
$29,196.90
R131964-100g
100g
In stock
$105,107.90

Reversible sodium ion influx inhibitor. Long-acting amide local anaesthetic agent.

Basic Description

SynonymsLEA 103 | ROPIVACAINE HYDROCHLORIDE MONOHYDRATE [EP IMPURITY] | Ropivacaine hydrochloride monohydrate, >=98% (HPLC) | NSC 15747 | Ropivacaine hydrochloride monohydrate; (-)-(2S)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride monohyd
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsRopivacaine Hydrochloride Monohydrate causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.Reversible sodium ion influx inhibitor. Long-acting a
Storage TempStore at 2-8°C
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Ropivacaine hydrochloride monohydrate is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
A reversible blockade of impulse propagation

Names and Identifiers

IUPAC Name (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrate;hydrochloride
INCHI InChI=1S/C17H26N2O.ClH.H2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H;1H2/t15-;;/m0../s1
InChi Key VSHFRHVKMYGBJL-CKUXDGONSA-N
Canonical SMILES CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl
Isomeric SMILES CCCN1CCCC[C@H]1C(=O)NC2=C(C=CC=C2C)C.O.Cl
WGK Germany 3
Alternate CAS 132112-35-7
PubChem CID 6918111
MeSH Entry Terms 1 Propyl 2',6' pipecoloxylidide;1-propyl-2',6'-pipecoloxylidide;AL 381;AL-381;AL381;LEA 103;LEA-103;LEA103;Naropeine;Naropin;ropivacaine;ropivacaine hydrochloride;ropivacaine monohydrochloride;ropivacaine monohydrochloride, (S)-isomer
Molecular Weight 328.88

Certificates

C of A & Other Certificates

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
D2418222Certificate of AnalysisMar 26, 2024 R131964
D2418238Certificate of AnalysisMar 26, 2024 R131964
D2418239Certificate of AnalysisMar 26, 2024 R131964
J2122221Certificate of AnalysisAug 21, 2023 R131964
J2122300Certificate of AnalysisAug 21, 2023 R131964
J2122301Certificate of AnalysisAug 21, 2023 R131964
J2122349Certificate of AnalysisAug 21, 2023 R131964
K1629029Certificate of AnalysisJun 14, 2022 R131964
H1802130Certificate of AnalysisApr 27, 2022 R131964

Chemical and Physical Properties

SolubilitySolubility: Soluble in DMSO (≥10mg/mL), methanol and water
Specific Rotation[α][α]/D -9 to -12, c = 1 in methanol

Safety and Hazards(GHS)

Pictogram(s) GHS05
Signal Danger
Hazard Statements

H318:Causes serious eye damage

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

WGK Germany 3

Related Documents

Citations of This Product(1)

1. Haiyan Wang, Yu Zhang, Xiaotao Xu, Aizhong Wang.  (2021)  An injectable mesoporous silica-based analgesic delivery system prolongs the duration of sciatic nerve block in mice with minimal toxicity.  Acta Biomaterialia,  135  (638).  [PMID:34520884] [10.1016/j.actbio.2021.09.008]

References

1. Haiyan Wang, Yu Zhang, Xiaotao Xu, Aizhong Wang.  (2021)  An injectable mesoporous silica-based analgesic delivery system prolongs the duration of sciatic nerve block in mice with minimal toxicity.  Acta Biomaterialia,  135  (638).  [PMID:34520884] [10.1016/j.actbio.2021.09.008]

Solution Calculators