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Roxatidine Acetate HCl - ≥99%, high purity , CAS No.93793-83-0

  • ≥99%
Item Number
R129246
Grouped product items
SKUSizeAvailabilityPrice Qty
R129246-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$30.90
R129246-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$127.90
R129246-5g
5g
In stock
$365.90
R129246-25g
25g
In stock
$1,647.90

Selective, competitive H 2 receptor antagonist

View related series
Pharmaceutical ingredients

Basic Description

Synonymsroxatidine acetate hydrochloride|93793-83-0|ROXATIDINE ACETATE HCl|Altat|Gastralgin|HOE 760|TZU-0460|Hoe-760|Roxatidine (Acetate Hydrochloride)|Pifatidine hydrochloride|NSC-760384|DTXSID2046670|HOE 062 [ROXATIDINE]|60426GOR1E|2-Acetoxy-N-(3-(m-(1-piperidi
Specifications & Purity≥99%
Biochemical and Physiological MechanismsRoxatidine Acetate Hydrochloride is a histamine H2-receptor antagonist used in ulcer treatment. This compound has been found to inhibit platelet function in vitro.Selective, competitive H 2 receptor antagonist (IC 50 = 3.2μM). Inhibits platelet function.
Storage TempStore at 2-8°C
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Roxatidine Acetate HCl is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.
An antagonist of the histamine H2-receptor.

Associated Targets

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name [2-oxo-2-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]ethyl] acetate;hydrochloride
INCHI InChI=1S/C19H28N2O4.ClH/c1-16(22)25-15-19(23)20-9-6-12-24-18-8-5-7-17(13-18)14-21-10-3-2-4-11-21;/h5,7-8,13H,2-4,6,9-12,14-15H2,1H3,(H,20,23);1H
InChi Key FEWCTJHCXOHWNL-UHFFFAOYSA-N
Canonical SMILES CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2.Cl
Isomeric SMILES CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2.Cl
PubChem CID 56704
Molecular Weight 384.9

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
I2227658Certificate of AnalysisJul 10, 2024 R129246
I2227768Certificate of AnalysisJul 10, 2024 R129246
F1502096Certificate of AnalysisMay 11, 2023 R129246
G1901139Certificate of AnalysisFeb 07, 2023 R129246

Chemical and Physical Properties

SolubilityDMSO 77 mg/mL Water 77 mg/mL Ethanol 12 mg/mL
Melt Point(°C)148 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

Merck Index 8274

Related Documents

Solution Calculators