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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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R129246-200mg | 200mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $30.90 | |
R129246-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $127.90 | |
R129246-5g | 5g | In stock | $365.90 | |
R129246-25g | 25g | In stock | $1,647.90 |
Selective, competitive H 2 receptor antagonist
Synonyms | roxatidine acetate hydrochloride|93793-83-0|ROXATIDINE ACETATE HCl|Altat|Gastralgin|HOE 760|TZU-0460|Hoe-760|Roxatidine (Acetate Hydrochloride)|Pifatidine hydrochloride|NSC-760384|DTXSID2046670|HOE 062 [ROXATIDINE]|60426GOR1E|2-Acetoxy-N-(3-(m-(1-piperidi |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Roxatidine Acetate Hydrochloride is a histamine H2-receptor antagonist used in ulcer treatment. This compound has been found to inhibit platelet function in vitro.Selective, competitive H 2 receptor antagonist (IC 50 = 3.2μM). Inhibits platelet function. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Roxatidine Acetate HCl is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | [2-oxo-2-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]ethyl] acetate;hydrochloride |
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INCHI | InChI=1S/C19H28N2O4.ClH/c1-16(22)25-15-19(23)20-9-6-12-24-18-8-5-7-17(13-18)14-21-10-3-2-4-11-21;/h5,7-8,13H,2-4,6,9-12,14-15H2,1H3,(H,20,23);1H |
InChi Key | FEWCTJHCXOHWNL-UHFFFAOYSA-N |
Canonical SMILES | CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2.Cl |
Isomeric SMILES | CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2.Cl |
PubChem CID | 56704 |
Molecular Weight | 384.9 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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I2227658 | Certificate of Analysis | Jul 10, 2024 | R129246 |
I2227768 | Certificate of Analysis | Jul 10, 2024 | R129246 |
F1502096 | Certificate of Analysis | May 11, 2023 | R129246 |
G1901139 | Certificate of Analysis | Feb 07, 2023 | R129246 |
Solubility | DMSO 77 mg/mL Water 77 mg/mL Ethanol 12 mg/mL |
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Melt Point(°C) | 148 °C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
Merck Index | 8274 |