S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt - ≥97%, high purity , CAS No.52248-03-0

  • ≥97%
Item Number
R341484
Grouped product items
SKUSizeAvailabilityPrice Qty
R341484-25mg
25mg
In stock
$57.90
R341484-100mg
100mg
In stock
$117.90
R341484-500mg
500mg
In stock
$570.90

a methyl donor and cofactor for enzyme-catalyzed methylations

Basic Description

SynonymsS-Adenosyl-L-methionine tosylate | S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt | J-010755 | R,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt | AdoMet | S-Adenosyl methionine tosylate;Ademetionine tosylate;AdoMet tosylate | S-(5'-Adenosyl)-L
Specifications & Purity≥97%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt is a methyl donor and cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). While present in all cells, S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt is concentrated in cells liver where 85% of all methylation reactions occur.


Product description:

S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt is used for the treatment of depression, liver cirrhosis, cholestasis and degenerative joint disease


Application:

S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt has been used for cell proliferation assay.[2] It has also been used for methylation assay


Names and Identifiers

IUPAC Name [(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium;4-methylbenzenesulfonate
INCHI InChI=1S/C15H22N6O5S.C7H8O3S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);2-5H,1H3,(H,8,9,10)/t7-,8+,10+,11+,14+,27?;/m0./s1
InChi Key VHPOFDUCFKOUHV-XKGORWRGSA-N
Canonical SMILES CC1=CC=C(C=C1)S(=O)(=O)[O-].C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
Isomeric SMILES CC1=CC=C(C=C1)S(=O)(=O)[O-].C[S+](CC[C@@H](C(=O)O)N)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O
PubChem CID 10153079
Molecular Weight 570.64

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6 results found

Lot NumberCertificate TypeDateItem
G23071009Certificate of AnalysisJun 02, 2023 R341484
G23071010Certificate of AnalysisJun 02, 2023 R341484
G23071011Certificate of AnalysisJun 02, 2023 R341484
G23071012Certificate of AnalysisJun 02, 2023 R341484
G2307964Certificate of AnalysisJun 02, 2023 R341484
G2307967Certificate of AnalysisJun 02, 2023 R341484

Chemical and Physical Properties

SolubilitySoluble in Water: 100 mg/mL
Melt Point(°C)70-90° C

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