Name: S-Acetylmercaptosuccinic anhydride - 96%, high purity , CAS No.6953-60-2
Price: 43.9 USD
Availability: InStock

Basic Description

Synonyms	6953-60-2\|S-Acetylmercaptosuccinic anhydride\|2-(Acetylthio)succinic anhydride\|Acetylthiosuccinic anhydride\|S-(2,5-dioxooxolan-3-yl) ethanethioate\|S-Acetylmercaptosuccinic acid anhydride\|Ethanethioic acid, S-(tetrahydro-2,5-dioxo-3-furanyl) ester\|Succinic
Specifications & Purity	≥96%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	S-Acetylmercaptosuccinic anhydride is an amine reactive reagent, containing a sulfhydryl group. The anhydride region opens up, when attacked by an amine nucleophile, forming amine linkage. However, during this ring opening reaction, a free carboxylate group is formed rendering the molecule negatively charged. Activity to proteins and conformation of the molecule us affected by the charge reversal.

Names and Identifiers

IUPAC Name	S-(2,5-dioxooxolan-3-yl) ethanethioate
INCHI	InChI=1S/C6H6O4S/c1-3(7)11-4-2-5(8)10-6(4)9/h4H,2H2,1H3
InChi Key	AHTFMWCHTGEJHA-UHFFFAOYSA-N
Canonical SMILES	CC(=O)SC1CC(=O)OC1=O
Isomeric SMILES	CC(=O)SC1CC(=O)OC1=O
PubChem CID	97914
Molecular Weight	174.17

Certificates

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Chemical and Physical Properties

Sensitivity	Moisture sensitive
Melt Point(°C)	83-86 °C (lit.)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.

References

1. M Better,S L Bernhard,S P Lei,D M Fishwild,S F Carroll. (1992-08-15) Activity of recombinant mitogillin and mitogillin immunoconjugates.. The Journal of biological chemistry, 267 ((23)): (16712-16718). [PMID:1644844]
2. Monica A Serban,Glenn D Prestwich. (2007-08-19) Synthesis of hyaluronan haloacetates and biology of novel cross-linker-free synthetic extracellular matrix hydrogels.. Biomacromolecules, 8 ((9)): (2821-2828). [PMID:17696398]
3. Olivier Flabeau,Imad Ghorayeb,Paul Perez,Aline Maillard,Jacques Taillard,Pierre Philip,Alexandra Foubert-Samier,François Tison,Wassilios G Meissner. (2016-12-25) Impact of sleep apnea syndrome on survival in patients with multiple system atrophy.. Parkinsonism & related disorders, 35 (92-95). [PMID:28011164]
4. Travis A Cos,Archana Bodas LaPollo,Mara Aussendorf,Jason M Williams,Kimberly Malayter,David S Festinger. (2019-09-15) Do Peer Recovery Specialists Improve Outcomes for Individuals with Substance Use Disorder in an Integrative Primary Care Setting? A Program Evaluation.. Journal of clinical psychology in medical settings, 27 ((4)): (704-715). [PMID:31520183]
5. Jonathan S Casey, Julien H Arrizabalaga, Mohammad Abu-Laban, Jeffrey C Becca, Benjamin J Rose, Kevin T Strickland, Jacob B Bursavich, Jacob S McCann, Carlos N Pacheco, Lasse Jensen, Anilchandra Attaluri, Daniel J Hayes,. (2020-03-27) Alternating magnetic field mediated release of fluorophores from magnetic nanoparticles by hysteretic heating.. Journal of colloid and interface science, ( 348-355 ). [PMID:32209489]
6. L Greenfield,W Bloch,M Moreland. (1990-11-01) Thiol-containing cross-linking agent with enhanced steric hindrance.. Bioconjugate chemistry, 1 ((6)): (400-410). [PMID:2129154]
7. T J Beveridge,R G Murray. (1980-02-01) Sites of metal deposition in the cell wall of Bacillus subtilis.. Journal of bacteriology, 141 ((2)): (876-887). [PMID:6767692]
8. Fabio Cannone,Giuseppe Chirico,Anna Rita Bizzarri,Salvatore Cannistraro. (2006-08-18) Quenching and blinking of fluorescence of a single dye molecule bound to gold nanoparticles.. The journal of physical chemistry. B, 110 ((33)): (16491-16498). [PMID:16913781]

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SKU	Size	Availability	Price
S468456-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$43.90
S468456-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$175.90
S468456-25g	25g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,000.90

S-Acetylmercaptosuccinic anhydride - 96%, high purity , CAS No.6953-60-2