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(S)-(+)-Epichlorohydrin - 98%, high purity , CAS No.67843-74-7

  • ≥98%
Item Number
E100521
Grouped product items
SKUSizeAvailabilityPrice Qty
E100521-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$9.90
E100521-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$13.90
E100521-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$37.90
E100521-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$133.90
E100521-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$600.90

Discover (S)-(+)-Epichlorohydrin by Aladdin Scientific in 98% for only $9.90. Available - in Ligands at Aladdin Scientific. Tags: asymmetric synthesis, Chiral non heterocyclic block.

Basic Description

Synonyms(S)-(+)-Epichlorohydrin|67843-74-7|(S)-Epichlorohydrin|(2S)-2-(chloromethyl)oxirane|(S)-2-(Chloromethyl)oxirane|(S)-(Chloromethyl)oxirane|Epichlorohydrin, (+)-|Oxirane, (chloromethyl)-, (2S)-|(+)-epichlorohydrin|SCR89B4R6O|s-epichlorohydrin|(S)-3-Chloropr
Specifications & Purity98%
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Product Description

Chiral building block in the enantioselective syntheses of hydroxyisoxazolidines and (+)-cis-sylvaticin, a potential antitumor agent.

Used in the total synthesis of Macquarimicinsand in the total synthesis of the macrolide RK-397.

Used to synthesize inhibitors of fatty acid oxidation as potential metabolic modulators.

Names and Identifiers

IUPAC Name (2S)-2-(chloromethyl)oxirane
INCHI InChI=1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2/t3-/m1/s1
InChi Key BRLQWZUYTZBJKN-GSVOUGTGSA-N
Canonical SMILES C1C(O1)CCl
Isomeric SMILES C1[C@H](O1)CCl
WGK Germany 3
RTECS RR0427100
PubChem CID 149428
UN Number 2023
Packing Group II
Molecular Weight 92.52
Beilstein 1420784
Reaxy-Rn 1420784

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

16 results found

Lot NumberCertificate TypeDateItem
G2403521Certificate of AnalysisApr 13, 2024 E100521
G2403522Certificate of AnalysisApr 13, 2024 E100521
G2403523Certificate of AnalysisApr 13, 2024 E100521
G1206050Certificate of AnalysisApr 07, 2024 E100521
F2327316Certificate of AnalysisJun 10, 2023 E100521
F2327332Certificate of AnalysisJun 10, 2023 E100521
F2327335Certificate of AnalysisJun 10, 2023 E100521
F2415053Certificate of AnalysisJun 10, 2023 E100521
B2318841Certificate of AnalysisOct 10, 2022 E100521
B2318858Certificate of AnalysisOct 10, 2022 E100521
B2318859Certificate of AnalysisOct 10, 2022 E100521
B2318860Certificate of AnalysisOct 10, 2022 E100521
B2215640Certificate of AnalysisJan 03, 2022 E100521
B2215712Certificate of AnalysisJan 03, 2022 E100521
B2215713Certificate of AnalysisJan 03, 2022 E100521
B2215715Certificate of AnalysisJan 03, 2022 E100521

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Chemical and Physical Properties

SolubilityMiscible with chloroform and methanol. Immiscible with water.
SensitivityMoisture sensitive.
Refractive Index1.4365-1.4385
Specific Rotation[α]45 ° (neat)
Flash Point(°F)89.6 °F
Flash Point(°C)33 °C
Boil Point(°C)114°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS05,   GHS07,   GHS02
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H311:Toxic in contact with skin

H331:Toxic if inhaled

H314:Causes severe skin burns and eye damage

H317:May cause an allergic skin reaction

H226:Flammable liquid and vapor

H330:Fatal if inhaled

H350:May cause cancer

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P270:Do not eat, drink or smoke when using this product.

P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P363:Wash contaminated clothing before reuse.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P320:Specific treatment is urgent (see ... on this label).

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P361+P364:Take off immediately all contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P318:if exposed or concerned, get medical advice.

WGK Germany 3
RTECS RR0427100
Reaxy-Rn 1420784
Class 6.1 / 3

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References

1. Munakata R, Katakai H, Ueki T, Kurosaka J, Takao K, Tadano K.  (2003)  Total synthesis of (+)-macquarimicin A..  J Am Chem Soc,  125  (48): (14722-3).  [PMID:14640644]
2. Svetlana A Burova,Frank E McDonald.  (2004-02-26)  Total synthesis of the polyene-polyol macrolide RK-397, featuring cross-couplings of alkynylepoxide modules..  Journal of the American Chemical Society,  126  ((8)): (2495-2500).  [PMID:14982459]
3. Elfatih Elzein,Kevin Shenk,Prabha Ibrahim,Tim Marquart,Suresh Kerwar,Stephanie Meyer,Hiba Ahmed,Dewan Zeng,Nancy Chu,Daniel Soohoo,Shirley Wong,Kwan Leung,Jeff Zablocki.  (2004-03-12)  Novel inhibitors of fatty acid oxidation as potential metabolic modulators..  Bioorganic & medicinal chemistry letters,  14  ((4)): (973-977).  [PMID:15013004]
4. Ryosuke Munakata,Hironori Katakai,Tatsuo Ueki,Jun Kurosaka,Ken-Ichi Takao,Kin-Ichi Tadano.  (2004-09-10)  Total synthesis of macquarimicins using an intramolecular Diels-Alder approach inspired by a biosynthetic pathway..  Journal of the American Chemical Society,  126  ((36)): (11254-11267).  [PMID:15355107]
5. Zheng-Yi Tao,Xin-Sheng Chai,Shu-Bin Wu.  (2011-08-05)  Determination of epichlorohydrin and 1,3-dichloro-2-propanol in synthesis of cationic etherifying reagent by headspace gas chromatography..  Journal of chromatography. A,  1218  ((37)): (6518-6521).  [PMID:21813132]
6. Rogério Laus,Valfredo Tadeu de Fávere.  (2011-08-10)  Competitive adsorption of Cu(II) and Cd(II) ions by chitosan crosslinked with epichlorohydrin-triphosphate..  Bioresource technology,  102  ((19)): (8769-8776).  [PMID:21824768]
7. Guang-Peng Wu,Sheng-Hsuan Wei,Wei-Min Ren,Xiao-Bing Lu,Tie-Qi Xu,Donald J Darensbourg.  (2011-08-23)  Perfectly alternating copolymerization of CO2 and epichlorohydrin using cobalt(III)-based catalyst systems..  Journal of the American Chemical Society,  133  ((38)): (15191-15199).  [PMID:21854028]
8. Masa-Aki Kawashiri,Atsushi Nohara,Tohru Noguchi,Hayato Tada,Chiaki Nakanishi,Mika Mori,Tetsuo Konno,Kenshi Hayashi,Noboru Fujino,Akihiro Inazu,Junji Kobayashi,Hiroshi Mabuchi,Masakazu Yamagishi.  (2011-11-25)  Efficacy and safety of coadministration of rosuvastatin, ezetimibe, and colestimide in heterozygous familial hypercholesterolemia..  The American journal of cardiology,  109  ((3)): (364-369).  [PMID:22112743]
9. Tamotsu Neda,Kouichi Inukai,Susumu Kurihara,Hiraku Ono,Toshio Hosaka,Hidetomo Nakamoto,Shigehiro Katayama,Takuya Awata.  (2012-01-11)  Hypoglycemic effects of colestimide on type 2 diabetic patients with obesity..  Endocrine journal,  59  ((3)): (239-246).  [PMID:22230809]
10. Tatsuya Suzuki,Kenzo Oba,Yoshimasa Igari,Kentaro Watanabe,Noriaki Matsumura,Shoko Futami-Suda,Motoshi Ouchi,Kazunari Suzuki,Ken-Ichi Sekimizu,Yoshiaki Kigawa,Hiroshi Nakano.  (2012-01-14)  Effects of bile-acid-binding resin (colestimide) on blood glucose and visceral fat in Japanese patients with type 2 diabetes mellitus and hypercholesterolemia: an open-label, randomized, case-control, crossover study..  Journal of diabetes and its complications,  26  ((1)): (34-39).  [PMID:22240263]
11. Jingyun Wang,Brian Yiu,Jaclyn Obermeyer,Carlos D M Filipe,John D Brennan,Robert Pelton.  (2012-01-20)  Effects of temperature and relative humidity on the stability of paper-immobilized antibodies..  Biomacromolecules,  13  ((2)): (559-564).  [PMID:22257068]
12. Elisabeth Eckert,Gabriele Leng,Wolfgang Gries,Thomas Göen.  (2012-02-22)  A method for the simultaneous determination of mercapturic acids as biomarkers of exposure to 2-chloroprene and epichlorohydrin in human urine..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  889-890  (69-76).  [PMID:22342446]
13. G Tataru,M Popa,D Costin,J Desbrieres.  (2012-02-22)  Microparticles based on natural and synthetic polymers for ophthalmic applications..  Journal of biomedical materials research. Part A,  100  ((5)): (1209-1220).  [PMID:22344747]
14. Resmi Anand,Francesco Manoli,Ilse Manet,Samia Daoud-Mahammed,Valentina Agostoni,Ruxandra Gref,Sandra Monti.  (2012-05-12)  β-Cyclodextrin polymer nanoparticles as carriers for doxorubicin and artemisinin: a spectroscopic and photophysical study..  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology,  11  ((8)): (1285-1292).  [PMID:22576059]
15. Huaxi Xiao,Qinlu Lin,Gao-Qiang Liu.  (2012-07-10)  Effect of cross-linking and enzymatic hydrolysis composite modification on the properties of rice starches..  Molecules (Basel, Switzerland),  17  ((7)): (8136-8146).  [PMID:22772809]
16. Seung Ree Seo,Mi Sun Lee,Byung Pil So,Jin-Chul Kim.  (2012-07-14)  In vivo pressure sore-healing efficacy of β-cyclodextrin/polyethyleneimine/silk fibroin xerogel..  International journal of dermatology,  51  ((8)): (987-995).  [PMID:22788820]
17. Celile Demirbilek,Cemile Özdemir Dinç.  (2012-07-31)  Synthesis of diethylaminoethyl dextran hydrogel and its heavy metal ion adsorption characteristics..  Carbohydrate polymers,  90  ((2)): (1159-1167).  [PMID:22840053]
18. Huo-Xi Jin,Zhong-Ce Hu,Yu-Guo Zheng.  (2012-08-28)  Enantioselective hydrolysis of epichlorohydrin using whole Aspergillus niger ZJB-09173 cells in organic solvents..  Journal of biosciences,  37  ((4)): (695-702).  [PMID:22922194]
19. Yu Yi,Li Zhu,Jianfeng Mei,Jianshu Chen,Guoqing Ying.  (2012-10-04)  IgG purification using affinity filtration with sulfamethazine-affinity carriers..  Preparative biochemistry & biotechnology,  42  ((6)): (598-610).  [PMID:23030470]
20. Ali Hebeish,M Hashem,M M Abd El-Hady,S Sharaf.  (2012-12-12)  Development of CMC hydrogels loaded with silver nano-particles for medical applications..  Carbohydrate polymers,  92  ((1)): (407-413).  [PMID:23218313]
21. Amalie E Donius,Marjorie A Kiechel,Caroline L Schauer,Ulrike G K Wegst.  (2013-01-26)  New crosslinkers for electrospun chitosan fibre mats. Part II: mechanical properties..  Journal of the Royal Society, Interface,  10  ((81)): (20120946-20120946).  [PMID:23349435]
22. Zahraalsadat Emami Meybodi,Mohammad Imani,Mohammad Atai.  (2013-02-13)  Kinetics of dextran crosslinking by epichlorohydrin: a rheometry and equilibrium swelling study..  Carbohydrate polymers,  92  ((2)): (1792-1798).  [PMID:23399221]
23. Aparna Roy,Sumit Chakraborty,Sarada Prasad Kundu,Subhasish Basu Majumder,Basudam Adhikari.  (2013-02-13)  Surface grafting of Corchorus olitorius fibre: a green approach for the development of activated bioadsorbent..  Carbohydrate polymers,  92  ((2)): (2118-2127).  [PMID:23399266]
24. Wensheng Lu,Yuhua Shen,Anjian Xie,Weiqiang Zhang.  (2013-03-27)  Preparation and protein immobilization of magnetic dialdehyde starch nanoparticles..  The journal of physical chemistry. B,  117  ((14)): (3720-3725).  [PMID:23528154]
25. Mariana Borsoi-Ribeiro,Igor Tadeu Lazzarotto Bresolin,Mookambeswaran Vijayalakshmi,Sônia Maria Alves Bueno.  (2013-09-03)  Behavior of human immunoglobulin G adsorption onto immobilized Cu(II) affinity hollow-fiber membranes..  Journal of molecular recognition : JMR,  26  ((10)): (514-520).  [PMID:23996494]
26. M Tajuddin Sikder,Md Shariful Islam,Tohru Kikuchi,Junichi Suzuki,Takeshi Saito,Masaaki Kurasaki.  (2014-05-24)  Removal of copper ions from water using epichlorohydrin cross-linked beta-cyclodextrin polymer: characterization, isotherms and kinetics..  Water environment research : a research publication of the Water Environment Federation,  86  ((4)): (296-304).  [PMID:24851325]
27. .  (2011-08-20)  Epichlorohydrin..  Report on carcinogens : carcinogen profiles,  12  (180-183).  [PMID:21852834]
28. Binbin Jiang,Wei Tao,Xin Lu,Yong Liu,Haibao Jin,Yan Pang,Xiaoyi Sun,Deyue Yan,Yongfeng Zhou.  (2012-03-15)  A POSS-based supramolecular amphiphile and its hierarchical self-assembly behaviors..  Macromolecular rapid communications,  33  ((9)): (767-772).  [PMID:22415982]
29. Mitsuhiro Watanabe,Kohkichi Morimoto,Sander M Houten,Nao Kaneko-Iwasaki,Taichi Sugizaki,Yasushi Horai,Chikage Mataki,Hiroyuki Sato,Karin Murahashi,Eri Arita,Kristina Schoonjans,Tatsuya Suzuki,Hiroshi Itoh,Johan Auwerx.  (2012-09-07)  Bile acid binding resin improves metabolic control through the induction of energy expenditure..  PloS one,  ((8)): (e38286-e38286).  [PMID:22952571]
30. Hua-Xi Xiao,Qin-Lu Lin,Gao-Qiang Liu,Feng-Xiang Yu.  (2012-09-14)  A comparative study of the characteristics of cross-linked, oxidized and dual-modified rice starches..  Molecules (Basel, Switzerland),  17  ((9)): (10946-10957).  [PMID:22971580]
31. Shunyi Li,Zhenjun Wu,Bin Li,Rencheng Zhu,Yan Wang.  (2012-10-04)  Chitosan resins synthesised by improved drop-sphere-forming method for Cr(VI) removal from aqueous solutions..  Water science and technology : a journal of the International Association on Water Pollution Research,  66  ((11)): (2461-2467).  [PMID:23032779]
32. Lei Guo,Guiying Li,Junshen Liu,Yanfeng Meng,Yanfeng Tang.  (2013-03-19)  Adsorptive decolorization of methylene blue by crosslinked porous starch..  Carbohydrate polymers,  93  ((2)): (374-379).  [PMID:23499071]
33. Ornanong S Kittipongpatana,Nisit Kittipongpatana.  (2013-06-26)  Physicochemical, in vitro digestibility and functional properties of carboxymethyl rice starch cross-linked with epichlorohydrin..  Food chemistry,  141  ((2)): (1438-1444).  [PMID:23790936]

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