| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| S357442-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $697.90 |
a metabolite of neuroamine reuptake inhibitor Venlafaxine
| Synonyms | (+)-Desvenlafaxine | AKOS030241085 | CS-0131893 | HY-B0602D | O-Desmethylvenlafaxine, (+)- | Phenol, 4-((1S)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)- | S-(+)-O-Desmethyl Venlafaxine | Q27251986 | 189BFR45S0 | (S)-(+)-O-Desmethyl Venlafaxine | Desv |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | S-(+)-O-Desmethyl Venlafaxine is a metabolite of Venlafaxine . Venlafaxine Hydrochloride is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake.|In vitro|studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4. |
| IUPAC Name | 4-[(1S)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol |
|---|---|
| INCHI | InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3/t15-/m1/s1 |
| InChi Key | KYYIDSXMWOZKMP-OAHLLOKOSA-N |
| Canonical SMILES | CN(C)CC(C1=CC=C(C=C1)O)C2(CCCCC2)O |
| Isomeric SMILES | CN(C)C[C@H](C1=CC=C(C=C1)O)C2(CCCCC2)O |
| PubChem CID | 9816723 |
| Molecular Weight | 263.38 |
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| Melt Point(°C) | 235-237° C |
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