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S-Trityl-L-cysteine - 97%, high purity , CAS No.2799-07-7

≥97%

CAS#: 2799-07-7
Formula: C₂₂H₂₁NO₂S
Molecular Weight: 363.47
Beilstein Registry Number: 2339626
EC Number: MFCD00002611
MDL number: MFCD00002611
PubChem CID: 76044
PubChem SID: 488185204

Item Number

T101029

Grouped product items
SKU	Size	Availability	Price
T101029-1g	1g	In stock	$11.90
T101029-5g	5g	In stock	$45.90
T101029-25g	25g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$205.90
T101029-100g	100g	In stock	$738.90
T101029-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$3,324.90

Potent, cell-permeable kinesin Eg5 inhibitor

View related series

Peptide chemistry Side chain protected amino acids

Basic Description

Synonyms	S-Trityl-L-cysteine\|2799-07-7\|H-Cys(Trt)-OH\|(+)-S-Trityl-L-cysteine\|S-Tritylcysteine\|Tritylcysteine\|NSC 83265\|S-(Triphenylmethyl)-L-cysteine\|3-Tritylthio-L-alanine\|STLC\|Alanine, 3-(tritylthio)-, L-\|(R)-2-amino-3-(tritylthio)propanoic acid\|(2R)-2-amino-3-[
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	Potent, cell-permeable kinesin Eg5 inhibitor (IC 50 = 140 nM). Blocks mitotic spindles and induces mitotic arrest in vitro . Antitumor and antimitotic agent. Active in vivo and in vitro .
Shipped In	Normal
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	(+)-S-Trityl-L-cysteine, a non-natural, sulfur-containing amino acid is commonly used as a reagent in solution phase peptide synthesis (SPPS). It is also used as a metal-binding agent to synthesize substituted ferrocenoyl peptide conjugates using HBTU peptide coupling reagent for the cation-sensing applications solution via peptide-metal interactions.

Associated Targets

CENPE Tchem Centromere-associated protein E 0 Activities

Discover Target: CENPE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KIF11 Tchem Kinesin-like protein KIF11 0 Activities

Discover Target: KIF11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KIF23 Tbio Kinesin-like protein KIF23 0 Activities

Discover Target: KIF23

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KIF4A Tbio Chromosome-associated kinesin KIF4A 0 Activities

Discover Target: KIF4A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488185204
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488185204
IUPAC Name	(2R)-2-amino-3-tritylsulfanylpropanoic acid
INCHI	InChI=1S/C22H21NO2S/c23-20(21(24)25)16-26-22(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,20H,16,23H2,(H,24,25)/t20-/m0/s1
InChi Key	DLMYFMLKORXJPO-FQEVSTJZSA-N
Canonical SMILES	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)SCC(C(=O)O)N
Isomeric SMILES	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)SC[C@@H](C(=O)O)N
WGK Germany	3
RTECS	AY7710000
PubChem CID	76044
Molecular Weight	363.47
Beilstein	2339626
Reaxy-Rn	2339626

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

9 results found

Lot Number	Certificate Type	Date	Item
I1516041	Certificate of Analysis	May 08, 2023	T101029
E2304372	Certificate of Analysis	Apr 13, 2023	T101029
H1520050	Certificate of Analysis	Apr 13, 2023	T101029
C2415125	Certificate of Analysis	Mar 02, 2022	T101029
C2427063	Certificate of Analysis	Mar 02, 2022	T101029
D2228037	Certificate of Analysis	Mar 02, 2022	T101029
D2228065	Certificate of Analysis	Mar 02, 2022	T101029
D2228069	Certificate of Analysis	Mar 02, 2022	T101029
D2304455	Certificate of Analysis	Mar 02, 2022	T101029

Chemical and Physical Properties

Specific Rotation[α]	111 ° (C=0.8, 0.04mol Ethanolic HCl)
Melt Point(°C)	182-183°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	AY7710000
Reaxy-Rn	2339626

References

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