(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone - >97.0%(GC), high purity , CAS No.346440-54-8

Item Number

S161185

• Synonyms: 346440-54-8 | (2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone | (2S,5S)-5-Benzyl-2-(tert-butyl)-3-methylimidazolidin-4-one | (2S,5S)-5-benzyl-2-tert-butyl-3-methylimidazolidin-4-one | 8LC842A6QP | Macmillan's imidazolidinone second generation catalyst |
• Specifications & Purity: >97.0%(GC)
• Shipped In: Normal

Product Description

product description：

(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone is a chiral imidazolidinone organocatalyst, developed by MacMillan and co-workers.

application：

(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone is a second-generation MacMillan catalyst, which can be used as a chiral organocatalyst in:

The chiral transformation reaction, including Friedel-Crafts and Mukaiyama-Michael reactions.

The preparation of substituted spiroundecenetriones via asymmetric domino Knoevenagel/Diels-Alder reactions.

The asymmetric synthesis of β-hydroxy aldehydes and their dimethylacetals via aldehyde-aldehyde aldol condensation reaction.

The enantioselective α-fluorination of aldehydes using N-fluorobenzenesulfonamide as a fluorinating agent.

The stereoselective preparation of (oxomethyl)oxabicyclo[3.2.1]octenones and tricyclic pyrroles via [4+3] cycloaddition of (trialkylsiloxy)pentadienals to furans.

Metal-free OrganoCatalyst technology for asymmetric catalysis. Catalyzes asymmetric indole alkylations, Friedel-Crafts alkylations, and a broad range of conjugate addition reactions in high enantiomeric excess.