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SA 57 - 98%, high purity , CAS No.1346169-63-8, Inhibitor of αβ-Hydrolase 6;Inhibitor of Fatty acid amide hydrolase;Inhibitor of Monoacylglycerol lipase

  • Moligand™
  • ≥98%
Item Number
S287063
Grouped product items
SKUSizeAvailabilityPrice Qty
S287063-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$166.90
S287063-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$409.90
S287063-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$700.90
S287063-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,129.90
S287063-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,150.90

Potent FAAH inhibitor

Basic Description

Synonyms4-[2-(4-Chlorophenyl)ethyl]-1-piperidinecarboxylic acid 2-(methylamino)-2-oxoethyl ester;(Z)-2-((4-(4-chlorophenethyl)piperidine-1-carbonyl)oxy)-N-methylacetimidic acid
Specifications & Purity98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of αβ-Hydrolase 6;Inhibitor of Fatty acid amide hydrolase;Inhibitor of Monoacylglycerol lipase

Associated Targets

FAAH Tchem Fatty-acid amide hydrolase 1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MGLL Tchem Monoglyceride lipase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABHD6 Tchem Monoacylglycerol lipase ABHD6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name [2-(methylamino)-2-oxoethyl] 4-[2-(4-chlorophenyl)ethyl]piperidine-1-carboxylate
INCHI InChI=1S/C17H23ClN2O3/c1-19-16(21)12-23-17(22)20-10-8-14(9-11-20)3-2-13-4-6-15(18)7-5-13/h4-7,14H,2-3,8-12H2,1H3,(H,19,21)
InChi Key JFSSVCSHPDLFCM-UHFFFAOYSA-N
Canonical SMILES CNC(=O)COC(=O)N1CCC(CC1)CCC2=CC=C(C=C2)Cl
Isomeric SMILES CNC(=O)COC(=O)N1CCC(CC1)CCC2=CC=C(C=C2)Cl
PubChem CID 44589122
Molecular Weight 338.83

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 8.47, Max Conc. mM: 25; Solvent:ethanol, Max Conc. mg/mL: 6.78, Max Conc. mM: 20

Related Documents

References

1. Niphakis MJ, Johnson DS, Ballard TE, Stiff C, Cravatt BF.  (2012)  O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors..  ACS Chem Neurosci,  (5): (418-26).  [PMID:22860211]

Solution Calculators