Sacubitrilat - 99%, high purity , CAS No.149709-44-4, Inhibitor of Neutral endopeptidase

Item Number

S412912

Grouped product items
SKU	Size	Availability	Price
S412912-5mg	5mg	In stock	$117.90
S412912-25mg	25mg	In stock	$434.90
S412912-100mg	100mg	In stock	$1,107.90
S412912-250mg	250mg	In stock	$2,493.90

Neprilysin Inhibitors

View related series

Basic Description

Synonyms	Sacubitrilat\|149709-44-4\|LBQ-657\|LBQ657\|(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid\|SPI5PBF81S\|CHEMBL417007\|(2R,4S)-5-(Biphenyl-4-yl)-4-((3-carboxypropionyl)amino)-2-methylpentanoic acid\|[1,1'-Biphenyl]-4-pentanoic aci
Specifications & Purity	Moligand™, ≥99%
Biochemical and Physiological Mechanisms	Sacubitrilat (Sac, LBQ-657) is an active inhibitor of neprilysin (NEP).
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of Neutral endopeptidase
Product Description	Information Sacubitrilat Sacubitrilat (Sac, LBQ-657) is an active inhibitor of neprilysin (NEP) . Targets NEP

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid
INCHI	InChI=1S/C22H25NO5/c1-15(22(27)28)13-19(23-20(24)11-12-21(25)26)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-10,15,19H,11-14H2,1H3,(H,23,24)(H,25,26)(H,27,28)/t15-,19+/m1/s1
InChi Key	DOBNVUFHFMVMDB-BEFAXECRSA-N
Canonical SMILES	CC(CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O)C(=O)O
Isomeric SMILES	C[C@H](C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O)C(=O)O
Alternate CAS	149709-44-4
PubChem CID	10430040
UN Number	2811
Packing Group	III
MeSH Entry Terms	LBQ657
Molecular Weight	383.44

Certificates

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot Number	Certificate Type	Date	Item
F2225438	Certificate of Analysis	Jun 01, 2022	S412912
F2225441	Certificate of Analysis	Jun 01, 2022	S412912
F2225442	Certificate of Analysis	Jun 01, 2022	S412912
F2225445	Certificate of Analysis	Jun 01, 2022	S412912

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Danger
Hazard Statements	H336:May cause drowsiness or dizziness H372:Causes damage to organs through prolonged or repeated exposure
Precautionary Statements	P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P314:Get medical advice/attention if you feel unwell. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P304+P340+P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing.Call a POISON CENTER or doctor. if you feel unwell.
Class	6.1
RIDADR	NONHforallmodesoftransport

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description