Grouped product items

SKU

Size

Availability

Price

Qty

S104171-10g

10g

In stock

$42.90

S104171-50g

50g

In stock

$179.90

S104171-250g

250g

Available within 4-8 weeks(?)

$1,440.90

Basic Description

Synonyms	A872074 \| BASIC RED 2 [INCI] \| CS-0010127 \| Mitsui safranine \| Phenazinium, 3,7-diamino-2,8-dimethyl-5-phenyl-, chloride (1:1) \| Safranine TH \| Safranine A \| Safranine Zh \| Brilliant safranine G \| S-0700 \| Basic Red 2 (Safranine O) \| Phenazinium,7-diamino
Specifications & Purity	indicator
Biochemical and Physiological Mechanisms	Biological stain used to stain Gram negative bacteria, chromosomes, mucin, cartilage and mast cells. Commonly used as a counter stain for gram-negative bacteria in the Gram stain procedure.
Shipped In	Normal
Grade	indicator
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Safranin T is a biological stain commonly used as a counter stain for gram-negative bacteria in the Gram stain procedure. Safranin T has been observed to bind to DNA at a pH 2.21. In the Flemming triple stain procedure Safranin T is used to stain for chromosomes. In late Palaeozoic pteridosperm cuticles Safranin T has shown increased contrast, emphasized cutinization differences, and enhanced the three-dimensional morphology of complex epidermal features when compared with other dyes. The compound has also been used with alcian blue in the histochemical study of the distribution and morphometric characteristics of mast cells. Safranin T has also been used to detect mucin and cartilage. A biological stain used to stain Gram negative bacteria, chormosomes, mucin, cartilage and mast cells.

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	3,7-dimethyl-10-phenylphenazin-10-ium-2,8-diamine;chloride
INCHI	InChI=1S/C20H18N4.ClH/c1-12-8-17-19(10-15(12)21)24(14-6-4-3-5-7-14)20-11-16(22)13(2)9-18(20)23-17;/h3-11H,1-2H3,(H3,21,22);1H
InChi Key	OARRHUQTFTUEOS-UHFFFAOYSA-N
Canonical SMILES	CC1=CC2=C(C=C1N)[N+](=C3C=C(C(=CC3=N2)C)N)C4=CC=CC=C4.[Cl-]
Isomeric SMILES	CC1=CC2=C(C=C1N)[N+](=C3C=C(C(=CC3=N2)C)N)C4=CC=CC=C4.[Cl-]
RTECS	SG1623000
PubChem CID	2723800
Molecular Weight	350.85
Beilstein	3924099
Reaxy-Rn	3924099

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot Number	Certificate Type	Date	Item
A2402565	Certificate of Analysis	Jan 10, 2024	S104171
A2402561	Certificate of Analysis	Jan 10, 2024	S104171
L2304372	Certificate of Analysis	Dec 18, 2023	S104171
J2311086	Certificate of Analysis	Oct 19, 2023	S104171
E23261025	Certificate of Analysis	Jun 05, 2023	S104171
B2328333	Certificate of Analysis	Mar 06, 2023	S104171
I2214263	Certificate of Analysis	Sep 20, 2022	S104171
I2214264	Certificate of Analysis	Sep 20, 2022	S104171
D2418055	Certificate of Analysis	Jul 30, 2022	S104171
G2227348	Certificate of Analysis	Jul 30, 2022	S104171
G2227351	Certificate of Analysis	Jul 30, 2022	S104171
G2219234	Certificate of Analysis	Jul 25, 2022	S104171
D23261139	Certificate of Analysis	Jul 16, 2022	S104171
G2213131	Certificate of Analysis	Jul 16, 2022	S104171
G2213129	Certificate of Analysis	Jul 16, 2022	S104171
G2213130	Certificate of Analysis	Jul 16, 2022	S104171
F2210673	Certificate of Analysis	Jun 15, 2022	S104171

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Chemical and Physical Properties

Solubility	Soluble in water (50 mg/ml at 20 °C), and alcohol
Sensitivity	Moisture sensitive.

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H318:Causes serious eye damage
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
RTECS	SG1623000
Reaxy-Rn	3924099

Citations of This Product

1. Lei Lei, Rui Cong, Yifei Ni, Xin Cui, Xulei Wang, Hongmei Ren, Zun Wang, Mengyuan Liu, Jiasheng Tu, Lei Jiang. (2023) Dual-Functional Injectable Hydrogel for Osteoarthritis Treatments. Advanced Healthcare Materials, (2302551). [PMID:37988224]
2. Kai Chen, Huiru Dong, Ziyi Ni, Yan Zhao, Yinyin Qian, Yuzhi Wang, Kaijia Xu. (2024) Selective extraction of anionic and cationic dyes using tailored hydrophobic deep eutectic solvents. TALANTA, 268 (125312). [PMID:37862754]
3. Dongxue Han, Guohua Li, Jie Wang, Teng Zheng, Liang Peng, Lin Li, Tifeng Jiao. (2023) Self-assembled composite Langmuir-Blodgett films of carbon nanotubes: An approach to enhance surface-enhanced Raman scattering and photoelectric performance. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 676 (132182). [PMID:]
4. Ning Liao, Bing Pang, Han Jin, Xixi Zhao, Dongyan Shao, Chunmei Jiang, Junling Shi. (2023) Modifications of Ganoderma lucidum spores into digestive-tissue highly adherent porous carriers with selective affinity to hydrophilic or hydrophobic drugs. BIOMATERIALS, 299 (122177). [PMID:37262935]
5. Lei Jin, An-Ni Zheng, Mei Wang, Jia-Qiang Yang, Zhao-Yun Wang, Fang-Zu Yang, De-Yin Wu, Dongping Zhan. (2023) Insights into the synergistic effects of safranine in an acidic copper bath on through-hole void-free filling for high-quality electronics interconnection. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 671 (131706). [PMID:]
6. Mao Xu, Qi Tang, Yuchen Liu, Jiaqi Shi, Weiyu Zhang, Chan Guo, Qiuwen Liu, Weiwei Lei, Cheng Chen. (2023) Charged Boron Nitride Nanosheet Membranes for Improved Organic Solvent Nanofiltration. ACS Applied Materials & Interfaces, 15 (9): (12524–12533). [PMID:36820819]
7. Zhixiao Liu, Zhiming Mi, Lingjun Meng, Yangyang Huang, Dexing Zhang, Junman Wang, Kaiyang Zhang, Jingling Xiao, Pingli Liu, Zhi Rao, Hongru He, Shuai Wang. (2023) Quaternary ammonium salts modification preparing charged Janus nanofiltration membrane for the simultaneous separation of divalent anions and cations. JOURNAL OF MEMBRANE SCIENCE, 672 (121440). [PMID:]
8. Zhiyong Qin, Kaiqiang Dong, Yidan Zhang, Yanling Jiang, Liuting Mo, Siyu Xiao. (2023) Noval green sodium alginate/gellan gum aerogel with 3D hierarchical porous structure for highly efficient and selective removal of Congo red from water. BIORESOURCE TECHNOLOGY, 370 (128576). [PMID:36603751]
9. Leilei Zang, Quhan Cheng, Shan Bai, Kai Wang, Xiaoyan Yuan. (2022) Electrospun membranes of carboxylated poly(ester urethane)urea/gelatin encapsulating pterostilbene for adaptive and antioxidative purposes. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, [PMID:36541432]
10. Qingqing Yu, Tong Shi, Zhiyu Xiong, Li Yuan, Hui Hong, Ruichang Gao, Yulong Bao. (2023) Oxidation affects dye binding of myofibrillar proteins via alteration in net charges mediated by a reduction in isoelectric point. FOOD RESEARCH INTERNATIONAL, 163 (112204). [PMID:36596136]
11. Guohua Li, Pengfei Bian, Ran Wang, Yan Li, Huiju Cao, Senlin Zhang, Zongshuo Hao, Mingli Wang, Tifeng Jiao. (2022) Preparation of composite Langmuir-Blodgett films based on carbon spheres and wide applications for acid/alkaline gas sensor, surface enhanced Raman scattering and photoelectrics. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 654 (130148). [PMID:]
12. Yuechun Li, Han Zhang, Zhaowen Cui, Sijie Liu, Jingke Xu, Conghui Jia, Yaqian Chen, Lulu Wang, Jing Sun, Daohong Zhang, Mingqiang Zhu, Jianlong Wang. (2023) Chemical staining enhanced Enzyme-linked immunosorbent assay for sensitive determination of Clenbuterol in food. FOOD CHEMISTRY, 400 (134012). [PMID:36055143]
13. Jiahui Wei, Hao Ren, Huamin Zhai, Shengcheng Zhai. (2022) Depolymerization behaviors of naked oat stem during autohydrolysis in mild subcritical water Ⅱ: Correlative changes in tissue structure, cell morphology, and chemical composition.. INDUSTRIAL CROPS AND PRODUCTS, 187 (115481). [PMID:]
14. Yuanting Xu, Wanting Lin, Dandan Yuan, Shifan Chen, Fang Li, Yanping Long, Chao He, Weifeng Zhao, Changsheng Zhao. (2022) “1+1>2”: Highly efficient removal of organic pollutants by composite nanofibrous membrane based on the synergistic effect of adsorption and photocatalysis. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 124 (76). [PMID:]
15. Chongling Wang, Na Li, Pengfei Bian, Guohua Li, Jingyue Yang, Qing Li, Tifeng Jiao. (2022) UV-response behavior and chiral structure determination of Langmuir-Blodgett films consisting of polypeptide and dye molecules. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 636 (128221). [PMID:]
16. Fangmeng Sheng, Xingya Li, Yuanyuan Li, Noor Ul Afsar, Zhang Zhao, Liang Ge, Tongwen Xu. (2022) Cationic covalent organic framework membranes for efficient dye/salt separation. JOURNAL OF MEMBRANE SCIENCE, 644 (120118). [PMID:]
17. Yang Liu, Xiaoping Zhang, Tengling Wu, Bo Liu, Jianhai Yang, Wenguang Liu. (2021) Chinese herb-crosslinked hydrogel bearing rBMSCs-laden polyzwitterion microgels: Self-adaptive manipulation of micromilieu and stemness maintenance for restoring infarcted myocardium. Nano Today, 41 (101306). [PMID:]

References

1. McKee AM et al.. (2021) Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth.. iScience, 24 (9): (103012). [PMID:34522855]
2. Lei Lei, Rui Cong, Yifei Ni, Xin Cui, Xulei Wang, Hongmei Ren, Zun Wang, Mengyuan Liu, Jiasheng Tu, Lei Jiang. (2023) Dual-Functional Injectable Hydrogel for Osteoarthritis Treatments. Advanced Healthcare Materials, (2302551). [PMID:37988224]
3. Kai Chen, Huiru Dong, Ziyi Ni, Yan Zhao, Yinyin Qian, Yuzhi Wang, Kaijia Xu. (2024) Selective extraction of anionic and cationic dyes using tailored hydrophobic deep eutectic solvents. TALANTA, 268 (125312). [PMID:37862754]
4. Dongxue Han, Guohua Li, Jie Wang, Teng Zheng, Liang Peng, Lin Li, Tifeng Jiao. (2023) Self-assembled composite Langmuir-Blodgett films of carbon nanotubes: An approach to enhance surface-enhanced Raman scattering and photoelectric performance. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 676 (132182). [PMID:]
5. Ning Liao, Bing Pang, Han Jin, Xixi Zhao, Dongyan Shao, Chunmei Jiang, Junling Shi. (2023) Modifications of Ganoderma lucidum spores into digestive-tissue highly adherent porous carriers with selective affinity to hydrophilic or hydrophobic drugs. BIOMATERIALS, 299 (122177). [PMID:37262935]
6. Lei Jin, An-Ni Zheng, Mei Wang, Jia-Qiang Yang, Zhao-Yun Wang, Fang-Zu Yang, De-Yin Wu, Dongping Zhan. (2023) Insights into the synergistic effects of safranine in an acidic copper bath on through-hole void-free filling for high-quality electronics interconnection. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 671 (131706). [PMID:]
7. Mao Xu, Qi Tang, Yuchen Liu, Jiaqi Shi, Weiyu Zhang, Chan Guo, Qiuwen Liu, Weiwei Lei, Cheng Chen. (2023) Charged Boron Nitride Nanosheet Membranes for Improved Organic Solvent Nanofiltration. ACS Applied Materials & Interfaces, 15 (9): (12524–12533). [PMID:36820819]
8. Zhixiao Liu, Zhiming Mi, Lingjun Meng, Yangyang Huang, Dexing Zhang, Junman Wang, Kaiyang Zhang, Jingling Xiao, Pingli Liu, Zhi Rao, Hongru He, Shuai Wang. (2023) Quaternary ammonium salts modification preparing charged Janus nanofiltration membrane for the simultaneous separation of divalent anions and cations. JOURNAL OF MEMBRANE SCIENCE, 672 (121440). [PMID:]
9. Zhiyong Qin, Kaiqiang Dong, Yidan Zhang, Yanling Jiang, Liuting Mo, Siyu Xiao. (2023) Noval green sodium alginate/gellan gum aerogel with 3D hierarchical porous structure for highly efficient and selective removal of Congo red from water. BIORESOURCE TECHNOLOGY, 370 (128576). [PMID:36603751]
10. Leilei Zang, Quhan Cheng, Shan Bai, Kai Wang, Xiaoyan Yuan. (2022) Electrospun membranes of carboxylated poly(ester urethane)urea/gelatin encapsulating pterostilbene for adaptive and antioxidative purposes. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, [PMID:36541432]
11. Qingqing Yu, Tong Shi, Zhiyu Xiong, Li Yuan, Hui Hong, Ruichang Gao, Yulong Bao. (2023) Oxidation affects dye binding of myofibrillar proteins via alteration in net charges mediated by a reduction in isoelectric point. FOOD RESEARCH INTERNATIONAL, 163 (112204). [PMID:36596136]
12. Guohua Li, Pengfei Bian, Ran Wang, Yan Li, Huiju Cao, Senlin Zhang, Zongshuo Hao, Mingli Wang, Tifeng Jiao. (2022) Preparation of composite Langmuir-Blodgett films based on carbon spheres and wide applications for acid/alkaline gas sensor, surface enhanced Raman scattering and photoelectrics. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 654 (130148). [PMID:]
13. Yuechun Li, Han Zhang, Zhaowen Cui, Sijie Liu, Jingke Xu, Conghui Jia, Yaqian Chen, Lulu Wang, Jing Sun, Daohong Zhang, Mingqiang Zhu, Jianlong Wang. (2023) Chemical staining enhanced Enzyme-linked immunosorbent assay for sensitive determination of Clenbuterol in food. FOOD CHEMISTRY, 400 (134012). [PMID:36055143]
14. Jiahui Wei, Hao Ren, Huamin Zhai, Shengcheng Zhai. (2022) Depolymerization behaviors of naked oat stem during autohydrolysis in mild subcritical water Ⅱ: Correlative changes in tissue structure, cell morphology, and chemical composition.. INDUSTRIAL CROPS AND PRODUCTS, 187 (115481). [PMID:]
15. Yuanting Xu, Wanting Lin, Dandan Yuan, Shifan Chen, Fang Li, Yanping Long, Chao He, Weifeng Zhao, Changsheng Zhao. (2022) “1+1>2”: Highly efficient removal of organic pollutants by composite nanofibrous membrane based on the synergistic effect of adsorption and photocatalysis. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 124 (76). [PMID:]
16. Chongling Wang, Na Li, Pengfei Bian, Guohua Li, Jingyue Yang, Qing Li, Tifeng Jiao. (2022) UV-response behavior and chiral structure determination of Langmuir-Blodgett films consisting of polypeptide and dye molecules. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 636 (128221). [PMID:]
17. Fangmeng Sheng, Xingya Li, Yuanyuan Li, Noor Ul Afsar, Zhang Zhao, Liang Ge, Tongwen Xu. (2022) Cationic covalent organic framework membranes for efficient dye/salt separation. JOURNAL OF MEMBRANE SCIENCE, 644 (120118). [PMID:]
18. Yang Liu, Xiaoping Zhang, Tengling Wu, Bo Liu, Jianhai Yang, Wenguang Liu. (2021) Chinese herb-crosslinked hydrogel bearing rBMSCs-laden polyzwitterion microgels: Self-adaptive manipulation of micromilieu and stemness maintenance for restoring infarcted myocardium. Nano Today, 41 (101306). [PMID:]

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Safranine T - indicator, high purity , CAS No.477-73-6