sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC 50 of 1.8 μM
In Vitro
sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose dependent manner, with an IC 50 of 1.8 μM. ?\nsAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.