| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| S477606-500μl | 500μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $178.90 |
| Specifications & Purity | ≥98%(HPLC), from Streptomyces albus |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Description Chemical structure: polyetherSalinomycin, Ready Made Solution has been used as an inhibitor of endocytosis in primary pancreatic tumor cells. It has also been used in sequential treatment of cancer cells to study resistance. Preparation instructions Form The product is supplied as a 2 mg/mL (2.66 mM) solution in DMSO, 0.2 μm-filtered. Principle |
Enter Lot Number to search for COA:
| Solubility | DMSO: soluble; H2O: insoluble; alcohols: soluble; carbon tetrachloride: soluble; chloroform: soluble; ethers and esters: soluble; hexane: soluble |
|---|
| 1. Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES. (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening.. Cell, 138 (4): (645-659). [PMID:19682730] [10.1021/op500134e] |
| 2. Hartmut Beug. (2009-08-26) Breast cancer stem cells: eradication by differentiation therapy?. Cell, 138 ((4)): (623-625). [PMID:19703390] |
| 3. Rosi Bissinger,Abaid Malik,Kashif Jilani,Florian Lang. (2014-04-11) Triggering of erythrocyte cell membrane scrambling by salinomycin.. Basic & clinical pharmacology & toxicology, 115 ((5)): (396-402). [PMID:24717091] |
| 4. Alessia Calzolari,Ernestina Saulle,Maria Laura De Angelis,Luca Pasquini,Alessandra Boe,Federica Pelacchi,Lucia Ricci-Vitiani,Marta Baiocchi,Ugo Testa. (2014-04-18) Salinomycin potentiates the cytotoxic effects of TRAIL on glioblastoma cell lines.. PloS one, 9 ((4)): (e94438-e94438). [PMID:24740347] |
| 5. Johannes Klose,Metodi V Stankov,Moritz Kleine,Wolf Ramackers,Diana Panayotova-Dimitrova,Mark D Jäger,Jürgen Klempnauer,Michael Winkler,Hüseyin Bektas,Georg M N Behrens,Florian W R Vondran. (2014-05-13) Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells.. PloS one, 9 ((5)): (e95970-e95970). [PMID:24816744] |
| 6. Dan Wang,Bijaya Upadhyaya,Yi Liu,David Knudsen,Moul Dey. (2014-08-17) Phenethyl isothiocyanate upregulates death receptors 4 and 5 and inhibits proliferation in human cancer stem-like cells.. BMC cancer, 14 (591-591). [PMID:25127663] |
| 7. Barbara Jonchère,Alexandra Vétillard,Bertrand Toutain,David Lam,Anne Charlotte Bernard,Cécile Henry,Sophie De Carné Trécesson,Erick Gamelin,Philippe Juin,Catherine Guette,Olivier Coqueret. (2015-01-08) Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1.. Oncotarget, 6 ((1)): (409-426). [PMID:25565667] |
| 8. Xueyan Zhang,Yuqing Lou,Huimin Wang,Xiaoxuan Zheng,Qianggang Dong,Jiayuan Sun,Baohui Han. (2015-03-04) Wnt signaling regulates the stemness of lung cancer stem cells and its inhibitors exert anticancer effect on lung cancer SPC-A1 cells.. Medical oncology (Northwood, London, England), 32 ((4)): (95-95). [PMID:25731617] |
| 9. Kwang-Youn Kim,Sang-Hun Kim,Sun-Nyoung Yu,Suel-Ki Park,Hyeun-Deok Choi,Hak-Sun Yu,Jae-Hoon Ji,Young-Kyo Seo,Soon-Cheol Ahn. (2015-04-22) Salinomycin enhances doxorubicin-induced cytotoxicity in multidrug resistant MCF-7/MDR human breast cancer cells via decreased efflux of doxorubicin.. Molecular medicine reports, 12 ((2)): (1898-1904). [PMID:25892525] |
| 10. Wojciech Senkowski,Xiaonan Zhang,Maria Hägg Olofsson,Ruben Isacson,Urban Höglund,Mats Gustafsson,Peter Nygren,Stig Linder,Rolf Larsson,Mårten Fryknäs. (2015-04-26) Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer.. Molecular cancer therapeutics, 14 ((6)): (1504-1516). [PMID:25911689] |
| 11. Jaganmohan R Jangamreddy,Mayur V Jain,Anna-Lotta Hallbeck,Karin Roberg,Kourosh Lotfi,Marek J Łos. (2015-04-29) Glucose starvation-mediated inhibition of salinomycin induced autophagy amplifies cancer cell specific cell death.. Oncotarget, 6 ((12)): (10134-10145). [PMID:25912307] |
| 12. Ravi Thakur,Rachana Trivedi,Namrata Rastogi,Manisha Singh,Durga Prasad Mishra. (2015-05-15) Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer.. Scientific reports, 5 (10194-10194). [PMID:25973915] |
| 13. Y H Kim,H B Lim. (2015-06-20) Laser-induced fluorescence reader with a turbidimetric system for sandwich-type immunoassay using nanoparticles.. Analytica chimica acta, 883 (32-36). [PMID:26088773] |
| 14. Agmal Scherzed,Stephan Hackenberg,Katrin Froelich,Kristen Rak,Christian Ginzkey,Rudolf Hagen,Philipp Schendzielorz,Norbert Kleinsasser. (2015-06-24) Effects of salinomycin and CGP37157 on head and neck squamous cell carcinoma cell lines in vitro.. Molecular medicine reports, 12 ((3)): (4455-4461). [PMID:26099997] |
| 15. Carmen Lidia Chitescu,George Kaklamanos,Anca Ioana Nicolau,Alida Adriana Maria Linda Stolker. (2015-06-24) High sensitive multiresidue analysis of pharmaceuticals and antifungals in surface water using U-HPLC-Q-Exactive Orbitrap HRMS. Application to the Danube river basin on the Romanian territory.. The Science of the total environment, 532 (501-511). [PMID:26100729] |
| 16. Miao He,Yingzi Fu,Yuanyuan Yan,Qinghuan Xiao,Huizhe Wu,Weifan Yao,Haishan Zhao,Lin Zhao,Qian Jiang,Zhaojin Yu,Feng Jin,Xiaoyi Mi,Enhua Wang,Zeshi Cui,Liwu Fu,Jianju Chen,Minjie Wei. (2015-07-23) The Hedgehog signalling pathway mediates drug response of MCF-7 mammosphere cells in breast cancer patients.. Clinical science (London, England : 1979), 129 ((9)): (809-822). [PMID:26201092] |
| 17. Hu Qu,Bo Ma,Hao-Feng Yuan,Zhong-Yang Wang,Sheng-Jie Guo,Jing Zhang. (2015-08-16) Effect of salinomycin on metastasis and invasion of bladder cancer cell line T24.. Asian Pacific journal of tropical medicine, 8 ((7)): (578-582). [PMID:26276292] |
| 18. Chang-Er Chen,Hao Zhang,Guang-Guo Ying,Li-Jun Zhou,Kevin C Jones. (2015-10-10) Passive sampling: A cost-effective method for understanding antibiotic fate, behaviour and impact.. Environment international, 85 (284-291). [PMID:26451705] |
| 19. Se Jin Oh,Kyung Hee Noh,Young-Ho Lee,Soon-Oh Hong,Kwon-Ho Song,Hyo-Jung Lee,Soyeon Kim,Tae Min Kim,Ju-Hong Jeon,Jae Hong Seo,Dong-Wan Kim,Tae Woo Kim. (2015-10-31) Targeting stemness is an effective strategy to control EML4-ALK+ non-small cell lung cancer cells.. Oncotarget, 6 ((37)): (40255-40267). [PMID:26517679] |
| 20. Ana Hidalgo-Sastre,Judit Desztics,Zahra Dantes,Katharina Schulte,Hilal Kabadayi Ensarioglu,Blessing Bassey-Archibong,Rupert Öllinger,Thomas Engleiter,Lyndsay Rayner,Henrik Einwächter,Juliet M Daniel,Ali Sameer Abdulghani Altaee,Katia Steiger,Marina Lesina,Roland Rad,Maximilian Reichert,Guido von Figura,Jens T Siveke,Roland M Schmid,Clara Lubeseder-Martellato. (2020-05-22) Loss of Wasl improves pancreatic cancer outcome.. JCI insight, 5 ((10)): [PMID:32434991] |
| 21. M Mitani,T Yamanishi,Y Miyazaki. (1975-10-27) Salinomycin: a new monovalent cation ionophore.. Biochemical and biophysical research communications, 66 ((4)): (1231-1236). [PMID:1191289] |
| 22. Dominik Fuchs,Andreas Heinold,Gerhard Opelz,Volker Daniel,Cord Naujokat. (2009-10-20) Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells.. Biochemical and biophysical research communications, 390 ((3)): (743-749). [PMID:19835841] |
| 23. Qiao Ming Zhi,Xue Hua Chen,Jun Ji,Jia Nian Zhang,Jian Fang Li,Qu Cai,Bing Ya Liu,Qin Long Gu,Zheng Gang Zhu,Ying Yan Yu. (2011-10-15) Salinomycin can effectively kill ALDH(high) stem-like cells on gastric cancer.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 65 ((7)): (509-515). [PMID:21996439] |
| 24. Wenyan Lu,Yonghe Li. (2014-06-07) Salinomycin suppresses LRP6 expression and inhibits both Wnt/β-catenin and mTORC1 signaling in breast and prostate cancer cells.. Journal of cellular biochemistry, 115 ((10)): (1799-1807). [PMID:24905570] |
| 25. Florian Kopp,Adam Hermawan,Prajakta Shirish Oak,Vijay Kumar Ulaganathan,Annika Herrmann,Nefertiti Elnikhely,Chitra Thakur,Zhiguang Xiao,Pjotr Knyazev,Beyhan Ataseven,Rajkumar Savai,Ernst Wagner,Andreas Roidl. (2014-12-17) Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells.. Translational oncology, 7 ((6)): (702-711). [PMID:25500079] |
| 26. Seon-Mi Yu,Song-Ja Kim. (2015-03-03) Salinomycin causes dedifferentiation via the extracellular signal-regulated kinase (ERK) pathway in rabbit articular chondrocytes.. Journal of pharmacological sciences, 127 ((2)): (196-202). [PMID:25727957] |
| 27. Masaya Kai,Noriko Kanaya,Shang V Wu,Carlos Mendez,Duc Nguyen,Thehang Luu,Shiuan Chen. (2015-04-24) Targeting breast cancer stem cells in triple-negative breast cancer using a combination of LBH589 and salinomycin.. Breast cancer research and treatment, 151 ((2)): (281-294). [PMID:25904215] |
| 28. Li-sen Qin,Pi-feng Jia,Zhi-qing Zhang,Shi-ming Zhang. (2015-05-31) ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis.. Journal of experimental & clinical cancer research : CR, 34 (57-57). [PMID:26024660] |
| 29. Maximilian Boesch,Alain G Zeimet,Holger Rumpold,Guenther Gastl,Sieghart Sopper,Dominik Wolf. (2015-07-03) Drug Transporter-Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics.. Stem cells translational medicine, 4 ((9)): (1028-1032). [PMID:26136502] |
| 30. Hyunsook An,Ji Young Kim,Nahyun Lee,Youngkwan Cho,Eunhye Oh,Jae Hong Seo. (2015-09-27) Salinomycin possesses anti-tumor activity and inhibits breast cancer stem-like cells via an apoptosis-independent pathway.. Biochemical and biophysical research communications, 466 ((4)): (696-703). [PMID:26407842] |
| 31. Sarah L Kessel,Leo Li-Ying Chan. (2020-05-13) A High-Throughput Image Cytometry Method for the Formation, Morphometric, and Viability Analysis of Drug-Treated Mammospheres.. SLAS discovery : advancing life sciences R & D, 25 ((7)): (723-733). [PMID:32396489] |
| 32. Brittney S Harrington,Michelle K Ozaki,Michael W Caminear,Lidia F Hernandez,Elizabeth Jordan,Nicholas J Kalinowski,Ian S Goldlust,Rajarshi Guha,Marc Ferrer,Craig Thomas,Jyoti Shetty,Bao Tran,Nathan Wong,Carrie D House,Christina M Annunziata. (2020-06-25) Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model.. Cancers, 12 ((6)): [PMID:32575908] |
