Name: SAM p-toluenesulfonate salt - 80%, high purity , CAS No.17176-17-9
Price: 145.9 USD
Availability: InStock

Basic Description

Synonyms	2-Amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonio)butanoate \| F82382 \| 2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate \| Ademetionine [US
Specifications & Purity	80%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Note	卖完停产，不再备货

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate
INCHI	InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/t7?,8-,10-,11-,14-,27?/m1/s1
InChi Key	MEFKEPWMEQBLKI-YDBXVIPQSA-N
Canonical SMILES	C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
Isomeric SMILES	C[S+](CCC(C(=O)[O-])N)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O
WGK Germany	3
Alternate CAS	52248-03-0
PubChem CID	9865603
Molecular Weight	398.44

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

WGK Germany	3

References

1. Guillermo A Senisterra,Hamed Ghanei,Galina Khutoreskaya,Elena Dobrovetsky,Aled M Edwards,Gilbert G Privé,Masoud Vedadi. (2010-02-13) Assessing the stability of membrane proteins to detect ligand binding using differential static light scattering.. Journal of biomolecular screening, 15 ((3)): (314-320). [PMID:20150591]
2. You Feng,Ranjan Maity,Julian P Whitelegge,Andrea Hadjikyriacou,Ziwei Li,Cecilia Zurita-Lopez,Qais Al-Hadid,Amander T Clark,Mark T Bedford,Jean-Yves Masson,Steven G Clarke. (2013-11-20) Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions.. The Journal of biological chemistry, 288 ((52)): (37010-37025). [PMID:24247247]
3. Le Thanh Mai Pham,Yong Hwan Kim. (2015-12-18) Discovery and characterization of new O-methyltransferase from the genome of the lignin-degrading fungus Phanerochaete chrysosporium for enhanced lignin degradation.. Enzyme and microbial technology, 82 (66-73). [PMID:26672450]
4. Jimmy Alarcan,Estelle Dubreil,Antoine Huguet,Romulo Aráoz,Françoise Brée,Belkacem Bouaita,Dominique Hurtaud-Pessel,Albert Braeuning,Stefanie Hessel-Pras,Alfonso Lampen,Ludovic Le Hégarat,Valérie Fessard. (2019-03-03) Metabolism of the lipophilic phycotoxin 13-Desmethylspirolide C using human and rat in vitro liver models.. Toxicology letters, 307 (17-25). [PMID:30825503]
5. Allison B Norvil,Lama AlAbdi,Bigang Liu,Yu Han Tu,Nicole E Forstoffer,Amie R Michie,Taiping Chen,Humaira Gowher. (2020-03-04) The acute myeloid leukemia variant DNMT3A Arg882His is a DNMT3B-like enzyme.. Nucleic acids research, 48 ((7)): (3761-3775). [PMID:32123902]
6. Susanne M Henning,Piwen Wang,Ru-Po Lee,Amy Trang,George Husari,Jieping Yang,Emma M Grojean,Austin Ly,Mark Hsu,David Heber,Tristan Grogan,Zhaoping Li,William J Aronson. (2020-04-30) Prospective randomized trial evaluating blood and prostate tissue concentrations of green tea polyphenols and quercetin in men with prostate cancer.. Food & function, 11 ((5)): (4114-4122). [PMID:32347270]
7. Jesús Rafael Rodríguez-Aguilera,Szilvia Ecsedi,Chloe Goldsmith,Marie-Pierre Cros,Mariana Domínguez-López,Nuria Guerrero-Celis,Rebeca Pérez-Cabeza de Vaca,Isabelle Chemin,Félix Recillas-Targa,Victoria Chagoya de Sánchez,Héctor Hernández-Vargas. (2020-05-10) Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor.. Scientific reports, 10 ((1)): (7822-7822). [PMID:32385352]
8. Gabriela Cruz-Carrillo,Larisa Montalvo-Martínez,Marcela Cárdenas-Tueme,Sofia Bernal-Vega,Roger Maldonado-Ruiz,Diana Reséndez-Pérez,Dalia Rodríguez-Ríos,Gertrud Lund,Lourdes Garza-Ocañas,Alberto Camacho-Morales. (2020-06-26) Fetal Programming by Methyl Donors Modulates Central Inflammation and Prevents Food Addiction-Like Behavior in Rats.. Frontiers in neuroscience, 14 (452-452). [PMID:32581665]
9. Ling Li,Shuai Zhu,Wenjie Shu,Yueshuai Guo,Yusheng Guan,Juan Zeng,Haichao Wang,Longsen Han,Jiaqi Zhang,Xiaohui Liu,Chunling Li,Xiaojing Hou,Min Gao,Juan Ge,Chao Ren,Hao Zhang,Tim Schedl,Xuejiang Guo,Minjian Chen,Qiang Wang. (2020-10-18) Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation.. Molecular cell, 80 ((3)): (525-540). [PMID:33068521]
10. Xiaohu Guo,Annika Söderholm,Sandesh Kanchugal P,Geir V Isaksen,Omar Warsi,Ulrich Eckhard,Silvia Trigüis,Adolf Gogoll,Jon Jerlström-Hultqvist,Johan Åqvist,Dan I Andersson,Maria Selmer. (2021-02-11) Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family.. eLife, 10 [PMID:33567250]
11. Christopher D Dawson,Stephania M Irwin,Lindsey R F Backman,Chip Le,Jennifer X Wang,Vyshnavi Vennelakanti,Zhongyue Yang,Heather J Kulik,Catherine L Drennan,Emily P Balskus. (2021-03-28) Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.. Cell chemical biology, 28 ((9)): (1333-1346). [PMID:33773110]
12. Mahmoud Hajj Chehade,Ludovic Pelosi,Cameron David Fyfe,Laurent Loiseau,Bérengère Rascalou,Sabine Brugière,Katayoun Kazemzadeh,Chau-Duy-Tam Vo,Lidia Ciccone,Laurent Aussel,Yohann Couté,Marc Fontecave,Frédéric Barras,Murielle Lombard,Fabien Pierrel. (2019-01-29) A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone.. Cell chemical biology, 26 ((4)): (482-492). [PMID:30686758]
13. Soumi Ghosh,Ayesha M Patel,Timothy J Grunkemeyer,Arti B Dumbrepatil,Kelcie Zegalia,Robert T Kennedy,E Neil G Marsh. (2020-01-25) Interactions between Viperin, Vesicle-Associated Membrane Protein A, and Hepatitis C Virus Protein NS5A Modulate Viperin Activity and NS5A Degradation.. Biochemistry, 59 ((6)): (780-789). [PMID:31977203]
14. Yang-Liu Xia,Hui-Lin Pang,Shi-Yang Li,Yong Liu,Ping Wang,Guang-Bo Ge. (2020-09-01) Accurate and sensitive detection of Catechol-O-methyltransferase activity by liquid chromatography with fluorescence detection.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1157 (122333-122333). [PMID:32866920]
15. Tao Guo,Zhe Dai,Ke You,Shyue-Fang Battaglia-Hsu,Juan Feng,Fengliang Wang,Bao Li,Jian Yang,Zhen Li. (2021-03-24) S-adenosylmethionine upregulates the angiotensin receptor-binding protein ATRAP via the methylation of HuR in NAFLD.. Cell death & disease, 12 ((4)): (306-306). [PMID:33753727]

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SAM p-toluenesulfonate salt - 80%, high purity , CAS No.17176-17-9