Basic Description

Synonyms	SAPONIN \| 8047-15-2 \| NSC 104795 \| NSC-135029 \| BRN 0078682 \| Olean-29-al, 13,28-epoxy-3-((O-beta-D-glucopyranosyl-(1-3)-O-(beta-D-xylopyranosyl-(1-2))-O-beta-D-glucopyranosyl-(1-4)-O-(beta-D-glucopyranosyl-(1-2))-alpha-L-arabinopyranosyl)oxy)-16-hydroxy-, (3-beta,
Specifications & Purity	BioReagent, ≥10%
Storage Temp	Argon charged
Shipped In	Normal
Grade	BioReagent
Product Description	Saponin is a secondary metabolite that facilitates the penetration of proteins through the cell membrane. Studies indicate that saponins are amphipathic glycosides, which can act as hemolytic agents. Research indicates that Saponin displays antinociceptive, anti-inflammatory and antipyretic activities, which may be due to its nonglycosidic moiety, sapogenin. Saponin can also be used in environmental research to recover chromium and other metals from sludge samples. Additional studies indicate that Saponin is useful in immunoassays since it can stimulate the Th1 immune response and the production of cytotoxic T-lymphocytes in response to exogenous antigens. An amphipathic glycoside and surfactant

Names and Identifiers

IUPAC Name	(2R,4S,5R,10S,13R,14R,18S,20R)-10-[(2S,3R,4S,5S)-3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-2-hydroxy-4,5,9,9,13,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracosane-20-carbaldehyde
INCHI	InChI=1S/C58H94O27/c1-52(2)29-7-11-55(5)30(8-12-58-31-15-53(3,22-62)13-14-57(31,23-77-58)32(64)16-56(55,58)6)54(29,4)10-9-33(52)82-50-46(85-51-45(40(71)37(68)27(19-61)80-51)84-49-43(74)39(70)36(67)26(18-60)79-49)44(83-48-42(73)38(69)35(66)25(17-59)78-48)28(21-76-50)81-47-41(72)34(65)24(63)20-75-47/h22,24-51,59-61,63-74H,7-21,23H2,1-6H3/t24-,25-,26-,27-,28+,29?,30-,31+,32-,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45-,46-,47+,48-,49-,50+,51+,53-,54+,55-,56+,57?,58?/m1/s1
InChi Key	MAEBCGDGGATMSC-OSHGGGOQSA-N
Canonical SMILES	CC1(C2CCC3(C(C2(CCC1OC4C(C(C(CO4)OC5C(C(C(CO5)O)O)O)OC6C(C(C(C(O6)CO)O)O)O)OC7C(C(C(C(O7)CO)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)CCC91C3(CC(C2(C9CC(CC2)(C)C=O)CO1)O)C)C)C
Isomeric SMILES	C[C@]1(CCC23COC4([C@H]2C1)CC[C@@H]5[C@]6(CC[C@@H](C(C6CC[C@]5([C@@]4(C[C@H]3O)C)C)(C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C=O
PubChem CID	198016

Certificates

Certificate of Analysis(COA)

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Lot Number	Certificate Type	Date	Item
K2302073	Certificate of Analysis	Nov 03, 2023	S639548

Chemical and Physical Properties

Solubility	Soluble in water.
Sensitivity	Hygroscopic

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P319:Get medical help if you feel unwell.

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jie He, Youfa Xie, Junzhen Zhong, Wenrong Chen, Suqiong Fang, Xing Chen, Shengfeng Peng, Wei Liu, Chengmei Liu. (2023) Improving shikonin solubility and stability by encapsulation in natural surfactant-coated shikonin nanoparticles. JOURNAL OF FOOD SCIENCE, 88 (2): (825-836). [PMID:36625167] [10.1111/1750-3841.16445]
2. Xiaonan Chen, Yiqing Zou, Shuqi Zhang, Pengchao Fang, Shuxuan Li, Pengyu Li, Yingying Sun, Gang Yuan, Haiyan Hu. (2022) Multi-functional vesicles improve Helicobacter pylori eradication by a comprehensive strategy based on complex pathological microenvironment. Acta Pharmaceutica Sinica B, 12 (3498). [PMID:36176916] [10.1016/j.apsb.2022.05.014]
3. Xi Yang, Yuan-Yuan Zang, Sha Yang, Zhi-Gang Chen. (2020) Green and efficient removal of heavy metals from Porphyra haitanensis using natural deep eutectic solvents. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (7): (2930-2939). [PMID:33155677] [10.1002/jsfa.10925]
4. Guosong Xin, Miao Yu, Yang Hu, Shiyong Gao, Zheng Qi, Yuan Sun, Wenjing Yu, Jiaxin He, Yubin Ji. (2020) Effect of lycorine on the structure and function of hepatoma cell membrane in vitro and in vivo. BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, 34 (1): (104-114). [PMID:] [10.1080/13102818.2020.1719019]
5. Shengfeng Peng, Ziling Li, Liqiang Zou, Wei Liu, Chengmei Liu, David Julian McClements. (2018) Improving curcumin solubility and bioavailability by encapsulation in saponin-coated curcumin nanoparticles prepared using a simple pH-driven loading method. Food & Function, 9 (3): (1829-1839). [PMID:29517797] [10.1039/C7FO01814B]
6. Yao Huang, Fang Feng, Zhi-Gang Chen, Tao Wu, Zi-Han Wang. (2018) Green and efficient removal of cadmium from rice flour using natural deep eutectic solvents. FOOD CHEMISTRY, 244 (260). [PMID:29120780] [10.1016/j.foodchem.2017.10.060]

References

1. Jie He, Youfa Xie, Junzhen Zhong, Wenrong Chen, Suqiong Fang, Xing Chen, Shengfeng Peng, Wei Liu, Chengmei Liu. (2023) Improving shikonin solubility and stability by encapsulation in natural surfactant-coated shikonin nanoparticles. JOURNAL OF FOOD SCIENCE, 88 (2): (825-836). [PMID:36625167] [10.1111/1750-3841.16445]
2. Xiaonan Chen, Yiqing Zou, Shuqi Zhang, Pengchao Fang, Shuxuan Li, Pengyu Li, Yingying Sun, Gang Yuan, Haiyan Hu. (2022) Multi-functional vesicles improve Helicobacter pylori eradication by a comprehensive strategy based on complex pathological microenvironment. Acta Pharmaceutica Sinica B, 12 (3498). [PMID:36176916] [10.1016/j.apsb.2022.05.014]
3. Xi Yang, Yuan-Yuan Zang, Sha Yang, Zhi-Gang Chen. (2020) Green and efficient removal of heavy metals from Porphyra haitanensis using natural deep eutectic solvents. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (7): (2930-2939). [PMID:33155677] [10.1002/jsfa.10925]
4. Guosong Xin, Miao Yu, Yang Hu, Shiyong Gao, Zheng Qi, Yuan Sun, Wenjing Yu, Jiaxin He, Yubin Ji. (2020) Effect of lycorine on the structure and function of hepatoma cell membrane in vitro and in vivo. BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, 34 (1): (104-114). [PMID:] [10.1080/13102818.2020.1719019]
5. Shengfeng Peng, Ziling Li, Liqiang Zou, Wei Liu, Chengmei Liu, David Julian McClements. (2018) Improving curcumin solubility and bioavailability by encapsulation in saponin-coated curcumin nanoparticles prepared using a simple pH-driven loading method. Food & Function, 9 (3): (1829-1839). [PMID:29517797] [10.1039/C7FO01814B]
6. Yao Huang, Fang Feng, Zhi-Gang Chen, Tao Wu, Zi-Han Wang. (2018) Green and efficient removal of cadmium from rice flour using natural deep eutectic solvents. FOOD CHEMISTRY, 244 (260). [PMID:29120780] [10.1016/j.foodchem.2017.10.060]

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Saponin - BR,≥10%, high purity , CAS No.8047-15-2