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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
SKU | Size | Availability | Price | Qty |
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Ab175651-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $49.90 | |
Ab175651-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $249.90 | |
Ab175651-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $619.90 | |
Ab175651-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $989.90 |
Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
Product Name | Satralizumab (anti-IL-6Ra) - Primary antibody, specific to IL6R, Human IgG2 |
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Synonyms | Enspryng,RG-6168;RG6168;SA-237;SA237;sapelizumab (deprecated INN);satralizumab-mwge |
Specifications & Purity | Carrier Free, Recombinant, Low Endotoxin, Azide Free, Validated, ExactAb™, ≥95%(SDS-PAGE&SEC), Lot by Lot |
Specificity | IL6R |
Conjugation | Unconjugated |
Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
Action Type | ANTAGONIST |
Mechanism of action | Antibody of Interleukin-6 receptor |
Product Description | Satralizumab (anti-IL-6RA), a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab (anti-IL-6RA) prevents dTAA formation and progression in rattus norvegicus. Satralizumab (anti-IL-6RA) can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research. |
Isotype | Human IgG2 |
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Light Chain Type | kappa |
Purification Method | Protein A purified |
Form | Liquid |
Concentration | Lot by Lot |
Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
Shipped In | Ice chest + Ice pads |
Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
CAS | 1535963-91-7 |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IMGT/mAb-DB | 586 |
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Enter Lot Number to search for COA:
1. Heo YA. (2020) Satralizumab: First Approval.. Drugs, 80 (14): (1477-1482). [PMID:32797372] |