SB220025 - ≥95%, high purity , CAS No.165806-53-1, Inhibitor of mitogen-activated protein kinase 14

Item Number

S339040

• Synonyms: SB220025|sb 220025|165806-53-1|3erk|SB-220025|4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidin-2-amine|MX95H97VRG|4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE|CHEMBL274064|CHEBI:82713|4-[5-(4-fluorophenyl)-3-
• Specifications & Purity: Moligand™, ≥95%
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of mitogen-activated protein kinase 14

Product Description

SB220025 is a specific and potent human p38 mitogen-activated protein kinase. It has been shown to reduce the production of tumor necrosis factor induced by lipopolysaccharide. SB220025 has been found to reduce the expression of interleukin-1β and tumor necrosis factor-α and inhibit angiogenesis over the course of granuloma development. SB220025 has also been found to be capable of reducing inflammatory cytokine production, and thus could be a potential effective treatment for chronic proliferative inflammatory disease.