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SC-1 - 98%, high purity , CAS No.1313019-65-6

  • ≥98%
Item Number
S412668
Grouped product items
SKUSizeAvailabilityPrice Qty
S412668-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$46.90
S412668-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
S412668-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$224.90
S412668-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$449.90
S412668-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$719.90
S412668-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90
View related series
STAT inhibitor

Basic Description

Synonyms1313019-65-6 | E73479 | SCHEMBL15746582 | 3-[4-chloro-3-(trifluoromethyl)phenyl]-1-[4-(4-cyanophenoxy)phenyl]urea | 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea | AKOS032470290 | 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-(4-cy
Specifications & Purity≥98%
Biochemical and Physiological MechanismsSC-1 blocks STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular carcinoma cell lines. SC-1 is a derivative of the multiple tyrosine kinase inhibitor sorafenib.
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Information

SC-1 blocks STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular carcinoma cell lines. SC-1 is a derivative of the multiple tyrosine kinase inhibitor sorafenib.

Associated Targets

RAF1 Tclin RAF proto-oncogene serine/threonine-protein kinase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTPN6 Tchem Tyrosine-protein phosphatase non-receptor type 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

STAT3 Tchem Signal transducer and activator of transcription 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-(4-cyanophenoxy)phenyl]urea
INCHI InChI=1S/C21H13ClF3N3O2/c22-19-10-5-15(11-18(19)21(23,24)25)28-20(29)27-14-3-8-17(9-4-14)30-16-6-1-13(12-26)2-7-16/h1-11H,(H2,27,28,29)
InChi Key HVPZDXDXIQZKHU-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1C#N)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
Isomeric SMILES C1=CC(=CC=C1C#N)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
WGK Germany 3
PubChem CID 53327725
Molecular Weight 431.80

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
F2417438Certificate of AnalysisMar 06, 2024 S412668
F2417439Certificate of AnalysisMar 06, 2024 S412668
F2417453Certificate of AnalysisMar 06, 2024 S412668
F2417454Certificate of AnalysisMar 06, 2024 S412668
F2417455Certificate of AnalysisMar 06, 2024 S412668
F2417456Certificate of AnalysisMar 06, 2024 S412668
F2417458Certificate of AnalysisMar 06, 2024 S412668
F2417459Certificate of AnalysisMar 06, 2024 S412668
F2417460Certificate of AnalysisMar 06, 2024 S412668
F2417489Certificate of AnalysisMar 06, 2024 S412668
F2417490Certificate of AnalysisMar 06, 2024 S412668
F2417491Certificate of AnalysisMar 06, 2024 S412668

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Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H413:May cause long lasting harmful effects to aquatic life

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P501:Dispose of contents/container to ...

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3
RIDADR NONHforallmodesoftransport

Related Documents

Solution Calculators