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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S356867-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $86.90 | |
S356867-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $258.90 | |
S356867-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $449.90 | |
S356867-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,029.90 | |
S356867-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,437.90 | |
S356867-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,299.90 |
Synonyms | 262451-89-8|1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine|SC 22716|SC-22716|CHEMBL119054|Pyrrolidine, 1-[2-([1,1'-biphenyl]-4-yloxy)ethyl]-|GTPL9102|SCHEMBL1899201|DTXSID50438298|BDBM50085251|AKOS025295019|NCGC00165874-01|HY-118795|1-[2-(Biphenyl-4-yloxy)-ethyl |
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Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of Leukotriene A 4 hydrolase |
Product Description | Cell-permeable leukotriene A4 (LTA4) hydrolase inhibitor which suppresses the production of LTB4. It is implicated in the pathogenesis of many diseases including inflammatory bowel disease and psoriasis. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 1-[2-(4-phenylphenoxy)ethyl]pyrrolidine |
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INCHI | InChI=1S/C18H21NO/c1-2-6-16(7-3-1)17-8-10-18(11-9-17)20-15-14-19-12-4-5-13-19/h1-3,6-11H,4-5,12-15H2 |
InChi Key | PKUGRVAJRGZDJP-UHFFFAOYSA-N |
Canonical SMILES | C1CCN(C1)CCOC2=CC=C(C=C2)C3=CC=CC=C3 |
Isomeric SMILES | C1CCN(C1)CCOC2=CC=C(C=C2)C3=CC=CC=C3 |
WGK Germany | 3 |
PubChem CID | 10333202 |
Molecular Weight | 267.37 |
PubChem CID | 10333202 |
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ChEMBL Ligand | CHEMBL119054 |
BindingDB Ligand | 50085251 |
CAS Registry No. | 262451-89-8 |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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H2415514 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415515 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415516 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415517 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415518 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415519 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415520 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415521 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415522 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415523 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415524 | Certificate of Analysis | Apr 30, 2024 | S356867 |
H2415525 | Certificate of Analysis | Apr 30, 2024 | S356867 |
Solubility | Soluble in DMSO: 22 mg/mL |
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WGK Germany | 3 |
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RIDADR | NONHforallmodesoftransport |
1. Penning TD, Chandrakumar NS, Chen BB, Chen HY, Desai BN, Djuric SW, Docter SH, Gasiecki AF, Haack RA, Miyashiro JM et al.. (2000) Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase.. J Med Chem, 43 (4): (721-35). [PMID:10691697] |